1boe: Difference between revisions

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 ==STRUCTURE OF THE IGF BINDING DOMAIN OF THE INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-5 (IGFBP-5): IMPLICATIONS FOR IGF AND IGF-I RECEPTOR INTERACTIONS==
-<StructureSection load='1boe' size='340' side='right' caption='[[1boe]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+<StructureSection load='1boe' size='340' side='right'caption='[[1boe]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1boe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BOE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BOE FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1boe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BOE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BOE FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1boe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1boe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1boe RCSB], [http://www.ebi.ac.uk/pdbsum/1boe PDBsum]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1boe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1boe OCA], [https://pdbe.org/1boe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1boe RCSB], [https://www.ebi.ac.uk/pdbsum/1boe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1boe ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/IBP5_HUMAN IBP5_HUMAN]] IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
+[https://www.uniprot.org/uniprot/IBP5_HUMAN IBP5_HUMAN] IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bo/1boe_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bo/1boe_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1boe ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
@@ Line 25: / Line 27: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 1boe" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Insulin-like growth factor binding protein 3D structures|Insulin-like growth factor binding protein 3D structures]]
 == References ==
 <references/>
@@ Line 30: / Line 36: @@
 </StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Demuth, D]]
+[[Category: Large Structures]]
-[[Category: Georgescu, J]]
+[[Category: Demuth D]]
-[[Category: Grol, M]]
+[[Category: Georgescu J]]
-[[Category: Holak, T H]]
+[[Category: Grol M]]
-[[Category: Kalus, W]]
+[[Category: Holak TH]]
-[[Category: Lang, K]]
+[[Category: Kalus W]]
-[[Category: Renner, C]]
+[[Category: Lang K]]
-[[Category: Sanchez, Y]]
+[[Category: Renner C]]
-[[Category: Schumacherdony, C]]
+[[Category: Sanchez Y]]
-[[Category: Zweckstetter, M]]
+[[Category: Schumacherdony C]]
-[[Category: Hormone-growth factor complex]]
+[[Category: Zweckstetter M]]
-[[Category: Igf]]
-[[Category: Igfbp-5]]
-[[Category: Insulin-like growth factor binding protein]]
-[[Category: Mini-igfbp-5]]