1b4i: Difference between revisions

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==Control of K+ Channel Gating by protein phosphorylation: structural switches of the inactivation gate, NMR, 22 structures==
==Control of K+ Channel Gating by protein phosphorylation: structural switches of the inactivation gate, NMR, 22 structures==
<StructureSection load='1b4i' size='340' side='right' caption='[[1b4i]], [[NMR_Ensembles_of_Models | 23 NMR models]]' scene=''>
<StructureSection load='1b4i' size='340' side='right'caption='[[1b4i]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1b4i]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B4I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B4I FirstGlance]. <br>
<table><tr><td colspan='2'>[[1b4i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B4I FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 23 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b4i OCA], [http://pdbe.org/1b4i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1b4i RCSB], [http://www.ebi.ac.uk/pdbsum/1b4i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1b4i ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b4i OCA], [https://pdbe.org/1b4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b4i RCSB], [https://www.ebi.ac.uk/pdbsum/1b4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b4i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KCNC4_HUMAN KCNC4_HUMAN]] This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.  
[https://www.uniprot.org/uniprot/KCNC4_HUMAN KCNC4_HUMAN] This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 1b4i" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1b4i" style="background-color:#fffaf0;"></div>
==See Also==
*[[Potassium Channel|Potassium Channel]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Antz, C]]
[[Category: Homo sapiens]]
[[Category: Bauer, T]]
[[Category: Large Structures]]
[[Category: Baukrowitz, T]]
[[Category: Antz C]]
[[Category: Covarrubias, M]]
[[Category: Bauer T]]
[[Category: Fakler, B]]
[[Category: Baukrowitz T]]
[[Category: Frank, R]]
[[Category: Covarrubias M]]
[[Category: Kalbacher, H]]
[[Category: Fakler B]]
[[Category: Kalbitzer, H R]]
[[Category: Frank R]]
[[Category: Ruppersberg, J P]]
[[Category: Kalbacher H]]
[[Category: Inactivation gate]]
[[Category: Kalbitzer HR]]
[[Category: Phosphorylation]]
[[Category: Ruppersberg JP]]
[[Category: Potassium channel]]
[[Category: Proton transport]]

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