1b09: Difference between revisions

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OCA

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 ==HUMAN C-REACTIVE PROTEIN COMPLEXED WITH PHOSPHOCHOLINE==
-<StructureSection load='1b09' size='340' side='right' caption='[[1b09]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+<StructureSection load='1b09' size='340' side='right'caption='[[1b09]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1b09]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B09 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B09 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1b09]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B09 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B09 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b09 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b09 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b09 RCSB], [http://www.ebi.ac.uk/pdbsum/1b09 PDBsum]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b09 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b09 OCA], [https://pdbe.org/1b09 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b09 RCSB], [https://www.ebi.ac.uk/pdbsum/1b09 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b09 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/CRP_HUMAN CRP_HUMAN] Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b0/1b09_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b0/1b09_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1b09 ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
@@ Line 24: / Line 28: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 1b09" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[C-reactive protein|C-reactive protein]]
 == References ==
 <references/>
@@ Line 29: / Line 37: @@
 </StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Pepys, M B]]
+[[Category: Large Structures]]
-[[Category: Thompson, D]]
+[[Category: Pepys MB]]
-[[Category: Wood, S P]]
+[[Category: Thompson D]]
-[[Category: Acute-phase reactant]]
+[[Category: Wood SP]]
-[[Category: Immune system]]
-[[Category: Pentraxin]]
-[[Category: Phosphocholine]]