2ny6: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 ==HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, I109C, T123C, T257S, V275C,S334A, S375W, Q428C, G431C) Complexed with CD4 and Antibody 17b==
-<StructureSection load='2ny6' size='340' side='right' caption='[[2ny6]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
+<StructureSection load='2ny6' size='340' side='right'caption='[[2ny6]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2ny6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NY6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NY6 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2ny6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NY6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NY6 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SUC:SUCROSE'>SUC</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gc1|1gc1]], [[1rzj|1rzj]], [[1rzk|1rzk]], [[2nxy|2nxy]], [[2nxz|2nxz]], [[2ny0|2ny0]], [[2ny1|2ny1]], [[2ny2|2ny2]], [[2ny3|2ny3]], [[2ny4|2ny4]], [[2ny5|2ny5]], [[2ny7|2ny7]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ny6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ny6 OCA], [https://pdbe.org/2ny6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ny6 RCSB], [https://www.ebi.ac.uk/pdbsum/2ny6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ny6 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ny6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ny6 OCA], [http://pdbe.org/2ny6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ny6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ny6 PDBsum]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN]] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
+[https://www.uniprot.org/uniprot/Q8Q7Z9_9HIV1 Q8Q7Z9_9HIV1]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ny/2ny6_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ny/2ny6_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 31: / Line 31: @@
 ==See Also==
-*[[Antibody|Antibody]]
+*[[Antibody 3D structures|Antibody 3D structures]]
-*[[CD4|CD4]]
+*[[CD4 3D structures|CD4 3D structures]]
-*[[Gp120|Gp120]]
+*[[Gp120 3D structures|Gp120 3D structures]]
+*[[3D structures of human antibody|3D structures of human antibody]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Arthos, J]]
+[[Category: Human immunodeficiency virus 1]]
-[[Category: Burton, D R]]
+[[Category: Large Structures]]
-[[Category: Dey, B]]
+[[Category: Arthos J]]
-[[Category: Dimitrov, D S]]
+[[Category: Burton DR]]
-[[Category: Hessell, A J]]
+[[Category: Dey B]]
-[[Category: Kwong, P D]]
+[[Category: Dimitrov DS]]
-[[Category: Nabel, G J]]
+[[Category: Hessell AJ]]
-[[Category: Ryk, D Van]]
+[[Category: Kwong PD]]
-[[Category: Sodroski, J]]
+[[Category: Nabel GJ]]
-[[Category: Wyatt, R]]
+[[Category: Sodroski J]]
-[[Category: Xiang, S H]]
+[[Category: Van Ryk D]]
-[[Category: Xu, L]]
+[[Category: Wyatt R]]
-[[Category: Yang, X]]
+[[Category: Xiang SH]]
-[[Category: Zhang, M Y]]
+[[Category: Xu L]]
-[[Category: Zhou, T]]
+[[Category: Yang X]]
-[[Category: Zwick, M B]]
+[[Category: Zhang MY]]
-[[Category: Antibody]]
+[[Category: Zhou T]]
-[[Category: Cd4]]
+[[Category: Zwick MB]]
-[[Category: Gp120]]
-[[Category: Hiv]]
-[[Category: Viral protein-immune system complex]]