2hc0: Difference between revisions
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New page: left|200px<br /> <applet load="2hc0" size="450" color="white" frame="true" align="right" spinBox="true" caption="2hc0, resolution 1.3Å" /> '''Structure of HIV pro... |
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== | ==Structure of HIV protease 6X mutant in complex with AB-2.== | ||
<StructureSection load='2hc0' size='340' side='right'caption='[[2hc0]], [[Resolution|resolution]] 1.30Å' scene=''> | |||
[[ | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2hc0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HC0 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AB2:[1-((1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL)-1H-1,2,3-TRIAZOL-4-YL]METHYL+(1R,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YLCARBAMATE'>AB2</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hc0 OCA], [https://pdbe.org/2hc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hc0 RCSB], [https://www.ebi.ac.uk/pdbsum/2hc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hc0 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q9E3M8_HV1 Q9E3M8_HV1] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hc/2hc0_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hc0 ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Brik | [[Category: Brik A]] | ||
[[Category: Elder | [[Category: Elder JH]] | ||
[[Category: Heaslet | [[Category: Heaslet H]] | ||
[[Category: Lin | [[Category: Lin Y-C]] | ||
[[Category: Stout | [[Category: Stout CD]] | ||
Latest revision as of 12:45, 25 December 2024
Structure of HIV protease 6X mutant in complex with AB-2.Structure of HIV protease 6X mutant in complex with AB-2.
Structural highlights
FunctionEvolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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