2fht: Difference between revisions

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-{{Seed}}
-[[Image:2fht.png|left|200px]]
-<!--
+==Crystal Structure of Viral Macrophage Inflammatory Protein-II==
-The line below this paragraph, containing "STRUCTURE_2fht", creates the "Structure Box" on the page.
+<StructureSection load='2fht' size='340' side='right'caption='[[2fht]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2fht]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_8_strain_GK18 Human herpesvirus 8 strain GK18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FHT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FHT FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fht FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fht OCA], [https://pdbe.org/2fht PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fht RCSB], [https://www.ebi.ac.uk/pdbsum/2fht PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fht ProSAT]</span></td></tr>
-{{STRUCTURE_2fht|  PDB=2fht  |  SCENE=  }}
+</table>
+== Function ==
-===Crystal Structure of Viral Macrophage Inflammatory Protein-II===
+[https://www.uniprot.org/uniprot/VMI2_HHV8P VMI2_HHV8P] Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
-==About this Structure==
+Check<jmol>
-FHT is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FHT OCA].
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fh/2fht_consurf.spt"</scriptWhenChecked>
-==Reference==
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
-Crystal structure of chemically synthesized vMIP-II., Li Y, Liu D, Cao R, Kumar S, Dong C, An J, Wilson SR, Gao YG, Huang Z, Proteins. 2007 Apr 1;67(1):243-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17243149 17243149]
+    <text>to colour the structure by Evolutionary Conservation</text>
-[[Category: Single protein]]
+  </jmolCheckbox>
-[[Category: Cao, R.]]
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fht ConSurf].
-[[Category: Dong, C Z.]]
+<div style="clear:both"></div>
-[[Category: Gao, Y G.]]
+__TOC__
-[[Category: Huang, Z.]]
+</StructureSection>
-[[Category: Kumar, S.]]
+[[Category: Human herpesvirus 8 strain GK18]]
-[[Category: Li, Y.]]
+[[Category: Large Structures]]
-[[Category: Liu, D.]]
+[[Category: Cao R]]
-[[Category: Wilson, S R.]]
+[[Category: Dong CZ]]
-[[Category: Anti-hiv]]
+[[Category: Gao YG]]
-[[Category: Chemokine]]
+[[Category: Huang Z]]
-[[Category: Herpesvirus]]
+[[Category: Kumar S]]
+[[Category: Li Y]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 00:06:38 2008''
+[[Category: Liu D]]
+[[Category: Wilson SR]]