1ocu: Difference between revisions

 

==Crystal structure of the yeast PX-domain protein Grd19p (sorting nexin 3) complexed to phosphatidylinosytol-3-phosphate.==

<StructureSection load='1ocu' size='340' side='right'caption='[[1ocu]], [[Resolution|resolution]] 2.30&Aring;' scene=''>

<table><tr><td colspan='2'>[[1ocu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OCU FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=PIB:2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL+BUTANOATE'>PIB</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ocu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocu OCA], [https://pdbe.org/1ocu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ocu RCSB], [https://www.ebi.ac.uk/pdbsum/1ocu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ocu ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/SNX3_YEAST SNX3_YEAST] Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)).<ref>PMID:9456318</ref>  

     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oc/1ocu_consurf.spt"</scriptWhenChecked>

     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>

*[[Sorting nexin 3D structures|Sorting nexin 3D structures]]

[[Category: Large Structures]]

[[Category: Saccharomyces cerevisiae S288C]]

[[Category: Aufrere R]]

[[Category: Blondeau K]]

[[Category: Cheruel S]]

[[Category: Collinet B]]

[[Category: Graille M]]

[[Category: Henkes G]]

[[Category: Janin J]]

[[Category: Leulliot N]]

[[Category: Li de La Sierra-Gallay I]]

[[Category: Minard P]]

[[Category: Poupon A]]

[[Category: Savarin P]]

[[Category: Sorel I]]

[[Category: Zhou CZ]]

[[Category: De la Torre F]]

[[Category: Van Tilbeurgh H]]