1w6z: Difference between revisions

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-[[Image:1w6z.gif|left|200px]]<br />
-<applet load="1w6z" size="450" color="white" frame="true" align="right" spinBox="true"
-caption="1w6z, resolution 1.65&Aring;" />
-'''HIGH ENERGY TETRAGONAL LYSOZYME X-RAY STRUCTURE'''<br />
-==About this Structure==
+==High Energy Tetragonal Lysozyme X-ray Structure==
-W6Z is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ ]] with CL and HO3 as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Lysozyme Lysozyme]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W6Z OCA]].
+<StructureSection load='1w6z' size='340' side='right'caption='[[1w6z]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
-[[Category: Lysozyme]]
+== Structural highlights ==
-[[Category: Single protein]]
+<table><tr><td colspan='2'>[[1w6z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W6Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W6Z FirstGlance]. <br>
-[[Category: Aslantas, M.]]
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
-[[Category: Dimichiel, M.]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HO3:HOLMIUM+(III)+ATOM'>HO3</scene></td></tr>
-[[Category: Honkimaki, V.]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w6z OCA], [https://pdbe.org/1w6z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w6z RCSB], [https://www.ebi.ac.uk/pdbsum/1w6z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w6z ProSAT]</span></td></tr>
-[[Category: Jakoncic, J.]]
+</table>
-[[Category: Stojanoff, V.]]
+== Function ==
-[[Category: CL]]
+[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
-[[Category: HO3]]
+== Evolutionary Conservation ==
-[[Category: bacteriolytic enzyme]]
+[[Image:Consurf_key_small.gif|200px|right]]
-[[Category: direct protein sequencing]]
+Check<jmol>
-[[Category: energy]]
+  <jmolCheckbox>
-[[Category: glycosidase]]
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w6/1w6z_consurf.spt"</scriptWhenChecked>
-[[Category: high]]
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
-[[Category: holmium]]
+    <text>to colour the structure by Evolutionary Conservation</text>
-[[Category: hydrolase]]
+  </jmolCheckbox>
-[[Category: kedge]]
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w6z ConSurf].
-[[Category: lysozyme]]
+<div style="clear:both"></div>
-[[Category: signal]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 16:27:03 2007''
+==See Also==
+*[[Lysozyme 3D structures|Lysozyme 3D structures]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Gallus gallus]]
+[[Category: Large Structures]]
+[[Category: Aslantas M]]
+[[Category: Di Michiel M]]
+[[Category: Honkimaki V]]
+[[Category: Jakoncic J]]
+[[Category: Stojanoff V]]