2cm5: Difference between revisions

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<StructureSection load='2cm5' size='340' side='right'caption='[[2cm5]], [[Resolution|resolution]] 1.28&Aring;' scene=''>
<StructureSection load='2cm5' size='340' side='right'caption='[[2cm5]], [[Resolution|resolution]] 1.28&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2cm5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CM5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CM5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2cm5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CM5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CM5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.28&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1zbd|1zbd]], [[2chd|2chd]], [[2cm6|2cm6]], [[3rpb|3rpb]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cm5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cm5 OCA], [https://pdbe.org/2cm5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cm5 RCSB], [https://www.ebi.ac.uk/pdbsum/2cm5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cm5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cm5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cm5 OCA], [https://pdbe.org/2cm5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cm5 RCSB], [https://www.ebi.ac.uk/pdbsum/2cm5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cm5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/RP3A_RAT RP3A_RAT]] Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.  
[https://www.uniprot.org/uniprot/RP3A_RAT RP3A_RAT] Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cm/2cm5_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cm/2cm5_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Becker, S]]
[[Category: Rattus norvegicus]]
[[Category: Montaville, P]]
[[Category: Becker S]]
[[Category: Schlicker, C]]
[[Category: Montaville P]]
[[Category: Sheldrick, G M]]
[[Category: Schlicker C]]
[[Category: C2 domain]]
[[Category: Sheldrick GM]]
[[Category: C2a-c2b linker fragment]]
[[Category: C2b]]
[[Category: Ca2+ binding]]
[[Category: Metal-binding]]
[[Category: Protein transport]]
[[Category: Rabphilin3a]]
[[Category: Synapse]]
[[Category: Synaptic exocytosis]]
[[Category: Transport]]
[[Category: Zinc]]
[[Category: Zinc-finger]]

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