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==RAT PROCATHEPSIN B==
==RAT PROCATHEPSIN B==
<StructureSection load='1mir' size='340' side='right' caption='[[1mir]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1mir' size='340' side='right'caption='[[1mir]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1mir]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MIR FirstGlance]. <br>
<table><tr><td colspan='2'>[[1mir]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MIR FirstGlance]. <br>
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_B Cathepsin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.1 3.4.22.1] </span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mir OCA], [http://pdbe.org/1mir PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1mir RCSB], [http://www.ebi.ac.uk/pdbsum/1mir PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1mir ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mir OCA], [https://pdbe.org/1mir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mir RCSB], [https://www.ebi.ac.uk/pdbsum/1mir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mir ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CATB_RAT CATB_RAT]] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.  
[https://www.uniprot.org/uniprot/CATB_RAT CATB_RAT] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/1mir_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/1mir_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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</div>
</div>
<div class="pdbe-citations 1mir" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1mir" style="background-color:#fffaf0;"></div>
==See Also==
*[[Cathepsin 3D structures|Cathepsin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Large Structures]]
[[Category: Cathepsin B]]
[[Category: Rattus norvegicus]]
[[Category: Coulombe, R]]
[[Category: Coulombe R]]
[[Category: Cygler, M]]
[[Category: Cygler M]]
[[Category: Grochulski, P]]
[[Category: Grochulski P]]
[[Category: Mort, J S]]
[[Category: Mort JS]]
[[Category: Sivaraman, J]]
[[Category: Sivaraman J]]
[[Category: Storer, A C]]
[[Category: Storer AC]]
[[Category: Cysteine protease]]
[[Category: Hydrolase]]
[[Category: Thiol protease]]

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