2uz6: Difference between revisions
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==AChBP-targeted a-conotoxin correlates distinct binding orientations with nAChR subtype selectivity.== | ==AChBP-targeted a-conotoxin correlates distinct binding orientations with nAChR subtype selectivity.== | ||
<StructureSection load='2uz6' size='340' side='right' caption='[[2uz6]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='2uz6' size='340' side='right'caption='[[2uz6]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2uz6]] is a 20 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2uz6]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica] and [https://en.wikipedia.org/wiki/Conus_textile Conus textile]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UZ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UZ6 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
< | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uz6 OCA], [https://pdbe.org/2uz6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uz6 RCSB], [https://www.ebi.ac.uk/pdbsum/2uz6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uz6 ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q8WSF8_APLCA Q8WSF8_APLCA] | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uz/2uz6_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uz/2uz6_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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==See Also== | ==See Also== | ||
*[[Acetylcholine binding protein|Acetylcholine binding protein]] | *[[Acetylcholine binding protein 3D structures|Acetylcholine binding protein 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Aplysia californica]] | [[Category: Aplysia californica]] | ||
[[Category: | [[Category: Conus textile]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Alewood PF]] | ||
[[Category: | [[Category: Buttner R]] | ||
[[Category: Fish | [[Category: Dutertre S]] | ||
[[Category: Hopping | [[Category: Fish A]] | ||
[[Category: Kendel | [[Category: Hopping G]] | ||
[[Category: Lewis | [[Category: Kendel Y]] | ||
[[Category: Nicke | [[Category: Lewis RJ]] | ||
[[Category: Schroeder | [[Category: Nicke A]] | ||
[[Category: Sixma | [[Category: Schroeder C]] | ||
[[Category: Smit | [[Category: Sixma TK]] | ||
[[Category: Ulens | [[Category: Smit AB]] | ||
[[Category: | [[Category: Ulens C]] | ||
[[Category: Van Elk R]] | |||