1e80: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1e80.gif|left|200px]]<br />
-<applet load="1e80" size="450" color="white" frame="true" align="right" spinBox="true"
-caption="1e80, resolution 2.05&Aring;" />
-'''ENDOTHIAPEPSIN COMPLEX WITH RENIN INHIBITOR MERCK-KGAA-EMD56133'''<br />
-==About this Structure==
+==Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD56133==
-E80 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]] with MRM as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Mucorpepsin Mucorpepsin]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.23 3.4.23.23]]. Structure known Active Site: CAT. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1E80 OCA]].
+<StructureSection load='1e80' size='340' side='right'caption='[[1e80]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1e80]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E80 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E80 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0GQ:4-AMINO-N-{(1R,8R,9R,13R)-16-(4-AMINO-2-METHYLPYRIMIDIN-5-YL)-1-BENZYL-8-(CYCLOHEXYLMETHYL)-9-HYDROXY-13-[(1S)-1-METHYLPROPYL]-2,6,11,14-TETRAOXO-3,7,12,15-TETRAAZAHEXADEC-1-YL}PIPERIDINE-1-CARBOXAMIDE'>0GQ</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e80 OCA], [https://pdbe.org/1e80 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e80 RCSB], [https://www.ebi.ac.uk/pdbsum/1e80 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e80 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CARP_CRYPA CARP_CRYPA]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e8/1e80_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e80 ConSurf].
+<div style="clear:both"></div>
+==See Also==
+*[[Pepsin|Pepsin]]
+__TOC__
+</StructureSection>
 [[Category: Cryphonectria parasitica]]
-[[Category: Mucorpepsin]]
+[[Category: Large Structures]]
-[[Category: Single protein]]
+[[Category: Cooper JB]]
-[[Category: Cooper, J.B.]]
+[[Category: Raddatz P]]
-[[Category: Raddatz, P.]]
+[[Category: Read JA]]
-[[Category: Read, J.A.]]
+[[Category: Rippmann F]]
-[[Category: Rippmann, F.]]
+[[Category: Toldo L]]
-[[Category: Toldo, L.]]
-[[Category: MRM]]
-[[Category: hydrolase (acid proteinase)]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 15:07:55 2007''