1e81: Difference between revisions

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-[[Image:1e81.gif|left|200px]]<br />
-<applet load="1e81" size="450" color="white" frame="true" align="right" spinBox="true"
-caption="1e81, resolution 2.05&Aring;" />
-'''ENDOTHIAPEPSIN COMPLEX WITH RENIN INHIBITOR MERCK-KGAA-EMD61395'''<br />
-==About this Structure==
+==Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD61395==
-E81 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica] with MRM as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Mucorpepsin Mucorpepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.23 3.4.23.23] Structure known Active Site: CAT. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1E81 OCA].
+<StructureSection load='1e81' size='340' side='right'caption='[[1e81]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1e81]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E81 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E81 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M91:(2S)-1-{[(2R)-1-{[(2S,3S)-1-CYCLOHEXYL-3-HYDROXY-4-(2-OXOPYRIDIN-1(2H)-YL)BUTAN-2-YL]AMINO}-3-(METHYLSULFANYL)-1-OXOPROPAN-2-YL]AMINO}-1-OXO-3-PHENYLPROPAN-2-YL+4-AMINOPIPERIDINE-1-CARBOXYLATE'>M91</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e81 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e81 OCA], [https://pdbe.org/1e81 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e81 RCSB], [https://www.ebi.ac.uk/pdbsum/1e81 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e81 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CARP_CRYPA CARP_CRYPA]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e8/1e81_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e81 ConSurf].
+<div style="clear:both"></div>
+==See Also==
+*[[Pepsin|Pepsin]]
+__TOC__
+</StructureSection>
 [[Category: Cryphonectria parasitica]]
-[[Category: Mucorpepsin]]
+[[Category: Large Structures]]
-[[Category: Single protein]]
+[[Category: Cooper JB]]
-[[Category: Cooper, J.B.]]
+[[Category: Raddatz P]]
-[[Category: Raddatz, P.]]
+[[Category: Read JA]]
-[[Category: Read, J.A.]]
+[[Category: Rippmann F]]
-[[Category: Rippmann, F.]]
+[[Category: Toldo L]]
-[[Category: Toldo, L.]]
-[[Category: MRM]]
-[[Category: hydrolase (acid proteinase)]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov  5 16:07:51 2007''