3blb: Difference between revisions

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-[[Image:3blb.png|left|200px]]
-{{STRUCTURE_3blb|  PDB=3blb  |  SCENE=  }}
+==Crystal structure of Golgi Mannosidase II in complex with swainsonine at 1.3 Angstrom resolution==
+<StructureSection load='3blb' size='340' side='right'caption='[[3blb]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
-===Crystal structure of Golgi Mannosidase II in complex with swainsonine at 1.3 Angstrom resolution===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3blb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BLB FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SWA:1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL'>SWA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[3blb]] is a 1 chain structure of [[Mannosidase]] with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3blb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3blb OCA], [https://pdbe.org/3blb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3blb RCSB], [https://www.ebi.ac.uk/pdbsum/3blb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3blb ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/MAN2_DROME MAN2_DROME] Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bl/3blb_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3blb ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Mannosidase|Mannosidase]]
+*[[Mannosidase 3D structures|Mannosidase 3D structures]]
+__TOC__
+</StructureSection>
 [[Category: Drosophila melanogaster]]
-[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]
+[[Category: Large Structures]]
-[[Category: Kuntz, D A.]]
+[[Category: Kuntz DA]]
-[[Category: Rose, D R.]]
+[[Category: Rose DR]]
-[[Category: Glycosidase]]
-[[Category: Golgi apparatus]]
-[[Category: Golgi mannosidase]]
-[[Category: Hydrolase]]
-[[Category: Membrane]]
-[[Category: Signal-anchor]]
-[[Category: Transmembrane]]