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[[Image:2ra5.png|left|200px]]


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==Crystal structure of the putative transcriptional regulator from Streptomyces coelicolor==
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<StructureSection load='2ra5' size='340' side='right'caption='[[2ra5]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2ra5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor_A3(2) Streptomyces coelicolor A3(2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RA5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RA5 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SRT:S,R+MESO-TARTARIC+ACID'>SRT</scene></td></tr>
{{STRUCTURE_2ra5|  PDB=2ra5  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ra5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ra5 OCA], [https://pdbe.org/2ra5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ra5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ra5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ra5 ProSAT], [https://www.topsan.org/Proteins/MCSG/2ra5 TOPSAN]</span></td></tr>
 
</table>
===Crystal structure of the putative transcriptional regulator from Streptomyces coelicolor===
== Function ==
 
[https://www.uniprot.org/uniprot/Q9RKT6_STRCO Q9RKT6_STRCO]  
 
== Evolutionary Conservation ==
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==About this Structure==
  </jmolCheckbox>
2RA5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacteria Bacteria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RA5 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ra5 ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
In situ proteolysis for protein crystallization and structure determination., Dong A, Xu X, Edwards AM, Chang C, Chruszcz M, Cuff M, Cymborowski M, Di Leo R, Egorova O, Evdokimova E, Filippova E, Gu J, Guthrie J, Ignatchenko A, Joachimiak A, Klostermann N, Kim Y, Korniyenko Y, Minor W, Que Q, Savchenko A, Skarina T, Tan K, Yakunin A, Yee A, Yim V, Zhang R, Zheng H, Akutsu M, Arrowsmith C, Avvakumov GV, Bochkarev A, Dahlgren LG, Dhe-Paganon S, Dimov S, Dombrovski L, Finerty P Jr, Flodin S, Flores A, Graslund S, Hammerstrom M, Herman MD, Hong BS, Hui R, Johansson I, Liu Y, Nilsson M, Nedyalkova L, Nordlund P, Nyman T, Min J, Ouyang H, Park HW, Qi C, Rabeh W, Shen L, Shen Y, Sukumard D, Tempel W, Tong Y, Tresagues L, Vedadi M, Walker JR, Weigelt J, Welin M, Wu H, Xiao T, Zeng H, Zhu H, Nat Methods. 2007 Dec;4(12):1019-21. Epub 2007 Nov 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17982461 17982461]
</StructureSection>
[[Category: Bacteria]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Edwards AM]]
[[Category: Edwards, A M.]]
[[Category: Joachimiak A]]
[[Category: Joachimiak, A.]]
[[Category: Kim Y]]
[[Category: Kim, Y.]]
[[Category: Savchenko A]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Xu X]]
[[Category: Savchenko, A.]]
[[Category: Zheng H]]
[[Category: Xu, X.]]
[[Category: Zheng, H.]]
[[Category: Beta structure]]
[[Category: Dna-binding]]
[[Category: Mcsg]]
[[Category: Midwest center for structural genomic]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Utra domain]]
 
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