2qzd: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 ==Fitted structure of SCR4 of DAF into cryoEM density==
-<StructureSection load='2qzd' size='340' side='right' caption='[[2qzd]], [[Resolution|resolution]] 14.00&Aring;' scene=''>
+<SX load='2qzd' size='340' side='right' viewer='molstar' caption='[[2qzd]], [[Resolution|resolution]] 14.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2qzd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QZD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QZD FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2qzd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QZD FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD55, CR, DAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 14&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qzd OCA], [http://pdbe.org/2qzd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qzd RCSB], [http://www.ebi.ac.uk/pdbsum/2qzd PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qzd OCA], [https://pdbe.org/2qzd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qzd RCSB], [https://www.ebi.ac.uk/pdbsum/2qzd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qzd ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN]] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref>
+[https://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qz/2qzd_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qz/2qzd_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 27: / Line 28: @@
 </div>
 <div class="pdbe-citations 2qzd" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[CD55|CD55]]
 == References ==
 <references/>
 __TOC__
-</StructureSection>
+</SX>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Bowman, V D]]
+[[Category: Large Structures]]
-[[Category: Chipman, P R]]
+[[Category: Bator Kelly CM]]
-[[Category: Hafenstein, S]]
+[[Category: Bowman VD]]
-[[Category: Kelly, C M.Bator]]
+[[Category: Chipman PR]]
-[[Category: Lin, F]]
+[[Category: Hafenstein S]]
-[[Category: Medof, M E]]
+[[Category: Lin F]]
-[[Category: Rossmann, M G]]
+[[Category: Medof ME]]
-[[Category: Blood group antigen]]
+[[Category: Rossmann MG]]
-[[Category: Complement pathway]]
-[[Category: Glycoprotein]]
-[[Category: Gpi-anchor]]
-[[Category: Immune response]]
-[[Category: Immune system]]
-[[Category: Innate immunity]]
-[[Category: Lipoprotein]]
-[[Category: Membrane]]
-[[Category: Scr4 of daf from 1ojv fitted into cryoem density]]
-[[Category: Sushi]]