2qn5: Difference between revisions

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 ==Crystal Structure and Functional Study of the Bowman-Birk Inhibitor from Rice Bran in Complex with Bovine Trypsin==
-<StructureSection load='2qn5' size='340' side='right' caption='[[2qn5]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
+<StructureSection load='2qn5' size='340' side='right'caption='[[2qn5]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2qn5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QN5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QN5 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2qn5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Oryza_sativa_Japonica_Group Oryza sativa Japonica Group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QN5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QN5 FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1c2a|1c2a]], [[1tx6|1tx6]], [[1k9b|1k9b]], [[1s0q|1s0q]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qn5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qn5 OCA], [https://pdbe.org/2qn5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qn5 RCSB], [https://www.ebi.ac.uk/pdbsum/2qn5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qn5 ProSAT]</span></td></tr>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qn5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qn5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qn5 RCSB], [http://www.ebi.ac.uk/pdbsum/2qn5 PDBsum]</span></td></tr>
+</table>
-<table>
+== Function ==
+[https://www.uniprot.org/uniprot/IBBR_ORYSJ IBBR_ORYSJ]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qn/2qn5_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qn/2qn5_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qn5 ConSurf].
 <div style="clear:both"></div>
-<div style="background-color:#fffaf0;">
-== Publication Abstract from PubMed ==
-Bowman-Birk inhibitors (BBIs) are cysteine-rich proteins with inhibitory activity against proteases that are widely distributed in monocot and dicot species. The expression of rice BBI from Oryza sativa is up-regulated and induced by pathogens or insects during germination of rice seeds. The rice BBI (RBTI) of molecular weight 15 kDa has been crystallized using the hanging-drop vapour-diffusion method. According to the diffraction of rice BBI crystals at a resolution of 2.07 A, the unit cell belongs to space group P2(1)2(1)2(1), with unit-cell parameters a = 74.37, b = 96.69, c = 100.36 A. Preliminary analysis indicates four BBI molecules in an asymmetric unit, with a solvent content of 58.29%.
-Purification, crystallization and preliminary X-ray crystallographic analysis of rice Bowman-Birk inhibitor from Oryza sativa.,Lin YH, Li HT, Huang YC, Hsieh YC, Guan HH, Liu MY, Chang T, Wang AH, Chen CJ Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 1;62(Pt, 6):522-4. Epub 2006 May 5. PMID:16754971<ref>PMID:16754971</ref>
-From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-</div>
 ==See Also==
-*[[Trypsin|Trypsin]]
+*[[Trypsin 3D structures|Trypsin 3D structures]]
-== References ==
+*[[Trypsin inhibitor 3D structures|Trypsin inhibitor 3D structures]]
-<references/>
 __TOC__
 </StructureSection>
 [[Category: Bos taurus]]
-[[Category: Oryza sativa]]
+[[Category: Large Structures]]
-[[Category: Trypsin]]
+[[Category: Oryza sativa Japonica Group]]
-[[Category: Chen, C J.]]
+[[Category: Chen CJ]]
-[[Category: Guan, H H.]]
+[[Category: Guan HH]]
-[[Category: Hsieh, Y C.]]
+[[Category: Hsieh YC]]
-[[Category: Li, H T.]]
+[[Category: Li HT]]
-[[Category: Lin, Y H.]]
+[[Category: Lin YH]]
-[[Category: Wang, A H.J.]]
+[[Category: Wang AHJ]]
-[[Category: Bowman-birk inhibitor]]
-[[Category: Digestion]]
-[[Category: Hetero-dimer]]
-[[Category: Hydrolase]]
-[[Category: Hydrolase inhibitor-hydrolase complex]]
-[[Category: Metal-binding]]
-[[Category: Monocotyledonous plant]]
-[[Category: Plant-pest system]]
-[[Category: Protease inhibitor]]
-[[Category: Protease-inhibitor]]
-[[Category: Rbti]]
-[[Category: Reactive-site loop]]
-[[Category: Secreted]]
-[[Category: Serine protease inhibitor]]
-[[Category: Zymogen]]