2o5y: Difference between revisions

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==Crystal structure of the 1E9 LeuH47Trp/ArgH100Trp Fab progesterone complex==
==Crystal structure of the 1E9 LeuH47Trp/ArgH100Trp Fab progesterone complex==
<StructureSection load='2o5y' size='340' side='right' caption='[[2o5y]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
<StructureSection load='2o5y' size='340' side='right'caption='[[2o5y]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2o5y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O5Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O5Y FirstGlance]. <br>
<table><tr><td colspan='2'>[[2o5y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O5Y FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=STR:PROGESTERONE'>STR</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2o5x|2o5x]], [[2o5z|2o5z]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=STR:PROGESTERONE'>STR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o5y OCA], [http://pdbe.org/2o5y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2o5y RCSB], [http://www.ebi.ac.uk/pdbsum/2o5y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2o5y ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o5y OCA], [https://pdbe.org/2o5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o5y RCSB], [https://www.ebi.ac.uk/pdbsum/2o5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o5y ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o5/2o5y_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o5/2o5y_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Homo sapiens]]
[[Category: Verdino, P]]
[[Category: Large Structures]]
[[Category: Wilson, I A]]
[[Category: Mus musculus]]
[[Category: Antibody engineering]]
[[Category: Verdino P]]
[[Category: Chimeric fab]]
[[Category: Wilson IA]]
[[Category: Evolution of ligand recognition]]
[[Category: Immune system]]
[[Category: Immunoglobulin]]

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