2o3o: Difference between revisions

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-{{Seed}}
-[[Image:2o3o.png|left|200px]]
-<!--
+==Crystal Structure of the sensor histidine kinase regulator YycI from Bacillus subtitlis==
-The line below this paragraph, containing "STRUCTURE_2o3o", creates the "Structure Box" on the page.
+<StructureSection load='2o3o' size='340' side='right'caption='[[2o3o]], [[Resolution|resolution]] 2.89&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2o3o]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O3O FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.89&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-{{STRUCTURE_2o3o|  PDB=2o3o  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o3o OCA], [https://pdbe.org/2o3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o3o RCSB], [https://www.ebi.ac.uk/pdbsum/2o3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o3o ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/YYCI_BACSU YYCI_BACSU] Together with YycH, regulates the activity of the two-component system YycF/YycG.<ref>PMID:17307850</ref> <ref>PMID:18408157</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o3/2o3o_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o3o ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+YycI and YycH are two membrane-anchored periplasmic proteins that regulate the essential Bacillus subtilis YycG histidine kinase through direct interaction. Here we present the crystal structure of YycI at a 2.9-A resolution. YycI forms a dimer, and remarkably the structure resembles that of the two C-terminal domains of YycH despite nearly undetectable sequence homology (10%) between the two proteins.
-===Crystal Structure of the sensor histidine kinase regulator YycI from Bacillus subtitlis===
+The crystal structure of Bacillus subtilis YycI reveals a common fold for two members of an unusual class of sensor histidine kinase regulatory proteins.,Santelli E, Liddington RC, Mohan MA, Hoch JA, Szurmant H J Bacteriol. 2007 Apr;189(8):3290-5. Epub 2007 Feb 16. PMID:17307848<ref>PMID:17307848</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-<!--
+</div>
-The line below this paragraph, {{ABSTRACT_PUBMED_17307848}}, adds the Publication Abstract to the page
+<div class="pdbe-citations 2o3o" style="background-color:#fffaf0;"></div>
-(as it appears on PubMed at http://www.pubmed.gov), where 17307848 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_17307848}}
+__TOC__
+</StructureSection>
-==About this Structure==
-O3O is a 12 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O3O OCA].
-==Reference==
-<ref group="xtra">PMID:17307848</ref><references group="xtra"/>
 [[Category: Bacillus subtilis]]
-[[Category: Liddington, R C.]]
+[[Category: Large Structures]]
-[[Category: Santelli, E.]]
+[[Category: Liddington RC]]
-[[Category: Two-component system]]
+[[Category: Santelli E]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:26:05 2009''