2kjh: Difference between revisions

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 ==NMR based structural model of the UBCH8-UBIQUITIN complex==
-<StructureSection load='2kjh' size='340' side='right'caption='[[2kjh]], [[NMR_Ensembles_of_Models | 16 NMR models]]' scene=''>
+<StructureSection load='2kjh' size='340' side='right'caption='[[2kjh]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2kjh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KJH FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2kjh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KJH FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1wzv|1wzv]], [[1ubq|1ubq]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 16 models</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UBE2L6, UBCH8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), RPS27A UBA80, UBCEP1, UBA52, UBB, UBC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kjh OCA], [https://pdbe.org/2kjh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kjh RCSB], [https://www.ebi.ac.uk/pdbsum/2kjh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kjh ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquitin--protein_ligase Ubiquitin--protein ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.19 6.3.2.19] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kjh OCA], [http://pdbe.org/2kjh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kjh RCSB], [http://www.ebi.ac.uk/pdbsum/2kjh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2kjh ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/UB2L6_HUMAN UB2L6_HUMAN]] Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3.<ref>PMID:15131269</ref> <ref>PMID:16428300</ref> <ref>PMID:20508617</ref>
+[https://www.uniprot.org/uniprot/UB2L6_HUMAN UB2L6_HUMAN] Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3.<ref>PMID:15131269</ref> <ref>PMID:16428300</ref> <ref>PMID:20508617</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 16: / Line 14: @@
    <jmolCheckbox>
      <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kj/2kjh_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 32: / Line 30: @@
 ==See Also==
-*[[Ubiquitin|Ubiquitin]]
+*[[3D structures of ubiquitin|3D structures of ubiquitin]]
-*[[Ubiquitin conjugating enzyme|Ubiquitin conjugating enzyme]]
+*[[3D structures of ubiquitin conjugating enzyme|3D structures of ubiquitin conjugating enzyme]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Ubiquitin--protein ligase]]
+[[Category: Serniwka SA]]
-[[Category: Serniwka, S A]]
+[[Category: Shaw GS]]
-[[Category: Shaw, G S]]
-[[Category: Atp-binding]]
-[[Category: Cytoplasm]]
-[[Category: E2 enzyme]]
-[[Category: Haddock model]]
-[[Category: Isopeptide bond]]
-[[Category: Ligase]]
-[[Category: Ligase-protein binding complex]]
-[[Category: Nucleotide-binding]]
-[[Category: Nucleus]]
-[[Category: Protein-protein interaction]]
-[[Category: Ubl conjugation]]
-[[Category: Ubl conjugation pathway]]