2j4u: Difference between revisions

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<StructureSection load='2j4u' size='340' side='right'caption='[[2j4u]], [[Resolution|resolution]] 2.99&Aring;' scene=''>
<StructureSection load='2j4u' size='340' side='right'caption='[[2j4u]], [[Resolution|resolution]] 2.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2j4u]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J4U OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2J4U FirstGlance]. <br>
<table><tr><td colspan='2'>[[2j4u]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius] and [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J4U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J4U FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2j1n|2j1n]], [[1dtz|1dtz]], [[1i6q|1i6q]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.99&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2j4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j4u OCA], [http://pdbe.org/2j4u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j4u RCSB], [http://www.ebi.ac.uk/pdbsum/2j4u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2j4u ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j4u OCA], [https://pdbe.org/2j4u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j4u RCSB], [https://www.ebi.ac.uk/pdbsum/2j4u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j4u ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/OMPC_ECOLI OMPC_ECOLI]] Forms pores that allow passive diffusion of small molecules across the outer membrane. [[http://www.uniprot.org/uniprot/TRFL_CAMDR TRFL_CAMDR]] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate (By similarity).  The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity (By similarity).  
[https://www.uniprot.org/uniprot/OMPC_ECOLI OMPC_ECOLI] Forms pores that allow passive diffusion of small molecules across the outer membrane.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j4/2j4u_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j4/2j4u_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Acharya, R K]]
[[Category: Acharya RK]]
[[Category: Baalaji, S]]
[[Category: Baalaji S]]
[[Category: Krishnaswamy, S]]
[[Category: Krishnaswamy S]]
[[Category: Singh, T P]]
[[Category: Singh TP]]
[[Category: Antiacterial peptide]]
[[Category: Complex]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Ion transport]]
[[Category: Iron]]
[[Category: Iron transport]]
[[Category: Lactoferrin]]
[[Category: Membrane protein]]
[[Category: Membrane protein-hydrolase complex]]
[[Category: Membrane protein/hydrolase]]
[[Category: Metal-binding]]
[[Category: Ompc]]
[[Category: Porin]]
[[Category: Protease]]
[[Category: Serine protease]]
[[Category: Transport]]

Latest revision as of 08:17, 17 October 2024

E.coli OmpC - camel Lactoferrin complexE.coli OmpC - camel Lactoferrin complex

Structural highlights

2j4u is a 8 chain structure with sequence from Camelus dromedarius and Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.99Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

OMPC_ECOLI Forms pores that allow passive diffusion of small molecules across the outer membrane.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2j4u, resolution 2.99Å

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