2j3q: Difference between revisions

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OCA

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 ==Torpedo acetylcholinesterase complexed with fluorophore thioflavin T==
-<StructureSection load='2j3q' size='340' side='right' caption='[[2j3q]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
+<StructureSection load='2j3q' size='340' side='right'caption='[[2j3q]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2j3q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J3Q FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2j3q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetronarce_californica Tetronarce californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J3Q FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TFL:2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM'>TFL</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1acj|1acj]], [[1acl|1acl]], [[1amn|1amn]], [[1ax9|1ax9]], [[1cfj|1cfj]], [[1dx6|1dx6]], [[1e3q|1e3q]], [[1e66|1e66]], [[1ea5|1ea5]], [[1eea|1eea]], [[1eve|1eve]], [[1fss|1fss]], [[1gpk|1gpk]], [[1gpn|1gpn]], [[1gqr|1gqr]], [[1gqs|1gqs]], [[1h22|1h22]], [[1h23|1h23]], [[1hbj|1hbj]], [[1jga|1jga]], [[1jgb|1jgb]], [[1jjb|1jjb]], [[1oce|1oce]], [[1odc|1odc]], [[1qid|1qid]], [[1qie|1qie]], [[1qif|1qif]], [[1qig|1qig]], [[1qih|1qih]], [[1qii|1qii]], [[1qij|1qij]], [[1qik|1qik]], [[1qim|1qim]], [[1qti|1qti]], [[1som|1som]], [[1u65|1u65]], [[1ut6|1ut6]], [[1vot|1vot]], [[1vxo|1vxo]], [[1vxr|1vxr]], [[1w4l|1w4l]], [[1w6r|1w6r]], [[1w75|1w75]], [[1w76|1w76]], [[1zgb|1zgb]], [[1zgc|1zgc]], [[2ace|2ace]], [[2ack|2ack]], [[2c4h|2c4h]], [[2c58|2c58]], [[2c5f|2c5f]], [[2c5g|2c5g]], [[2cek|2cek]], [[2ckm|2ckm]], [[2cmf|2cmf]], [[2dfp|2dfp]], [[2j3d|2j3d]], [[3ace|3ace]], [[4ace|4ace]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TFL:2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM'>TFL</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j3q OCA], [https://pdbe.org/2j3q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j3q RCSB], [https://www.ebi.ac.uk/pdbsum/2j3q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j3q ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j3q OCA], [http://pdbe.org/2j3q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j3q RCSB], [http://www.ebi.ac.uk/pdbsum/2j3q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2j3q ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/ACES_TORCA ACES_TORCA]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.
+[https://www.uniprot.org/uniprot/ACES_TETCF ACES_TETCF] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 16: / Line 15: @@
    <jmolCheckbox>
      <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j3/2j3q_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 32: / Line 31: @@
 ==See Also==
-*[[AChE inhibitors and substrates|AChE inhibitors and substrates]]
 *[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]]
-*[[Acetylcholinesterase: Treatment of Alzheimer's disease|Acetylcholinesterase: Treatment of Alzheimer's disease]]
-*[[Journal:Protein Science:1|Journal:Protein Science:1]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Acetylcholinesterase]]
+[[Category: Large Structures]]
-[[Category: Torpedo californica]]
+[[Category: Tetronarce californica]]
-[[Category: Cusack, B]]
+[[Category: Cusack B]]
-[[Category: Harel, M]]
+[[Category: Harel M]]
-[[Category: Johnson, J L]]
+[[Category: Johnson JL]]
-[[Category: Rosenberry, T L]]
+[[Category: Rosenberry TL]]
-[[Category: Silman, I]]
+[[Category: Silman I]]
-[[Category: Sussman, J L]]
+[[Category: Sussman JL]]
-[[Category: Alternative splicing]]
-[[Category: Anticancer prodrug cpt- 11]]
-[[Category: Glycoprotein]]
-[[Category: Gpi-anchor]]
-[[Category: Hydrolase]]
-[[Category: Lipoprotein]]
-[[Category: Membrane]]
-[[Category: Neurotransmitter degradation]]
-[[Category: Serine esterase]]
-[[Category: Synapse]]
-[[Category: Torpedo ache]]