2gtf: Difference between revisions

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-{{Seed}}
-[[Image:2gtf.png|left|200px]]
-<!--
+==Crystal structure of nitrophorin 2 complex with pyrimidine==
-The line below this paragraph, containing "STRUCTURE_2gtf", creates the "Structure Box" on the page.
+<StructureSection load='2gtf' size='340' side='right'caption='[[2gtf]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2gtf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GTF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GTF FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=P1R:PYRIMIDINE'>P1R</scene></td></tr>
-{{STRUCTURE_2gtf|  PDB=2gtf  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gtf OCA], [https://pdbe.org/2gtf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gtf RCSB], [https://www.ebi.ac.uk/pdbsum/2gtf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gtf ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NP2_RHOPR NP2_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity).  Specifically inhibits factor IXa-catalyzed activation of factor X in the presence of calcium and phospholipids irrespective of the presence or absence of factor VIIIa.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gt/2gtf_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gtf ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of nitrophorin 2 complex with pyrimidine===
+==See Also==
+*[[Nitrophorin|Nitrophorin]]
+__TOC__
-==About this Structure==
+</StructureSection>
-GTF is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GTF OCA].
+[[Category: Large Structures]]
-==Reference==
-<ref group="xtra">PMID:10884386</ref><references group="xtra"/>
 [[Category: Rhodnius prolixus]]
-[[Category: Montfort, W R.]]
+[[Category: Montfort WR]]
-[[Category: Weichsel, A.]]
+[[Category: Weichsel A]]
-[[Category: Beta barrel]]
-[[Category: Ferric heme]]
-[[Category: Lipocalin]]
-[[Category: Pyrimidine]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:00:29 2009''