2gf3: Difference between revisions

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-[[Image:2gf3.png|left|200px]]
-{{STRUCTURE_2gf3|  PDB=2gf3  |  SCENE=  }}
+==Structure of the complex of monomeric sarcosine with its substrate analogue inhibitor 2-furoic acid at 1.3 A resolution.==
+<StructureSection load='2gf3' size='340' side='right'caption='[[2gf3]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
-===Structure of the complex of monomeric sarcosine with its substrate analogue inhibitor 2-furoic acid at 1.3 A resolution.===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2gf3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._(in:_Bacteria) Bacillus sp. (in: Bacteria)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GF3 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_10368302}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FOA:2-FUROIC+ACID'>FOA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf3 OCA], [https://pdbe.org/2gf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gf3 RCSB], [https://www.ebi.ac.uk/pdbsum/2gf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gf3 ProSAT]</span></td></tr>
-[[2gf3]] is a 2 chain structure of [[Sarcosine oxidase]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_sp. Bacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF3 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/MSOX_BACB0 MSOX_BACB0] Catalyzes the oxidative demethylation of sarcosine. Can also oxidize other secondary amino acids such as N-methyl-L-alanine.[HAMAP-Rule:MF_00516]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gf/2gf3_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gf3 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
 *[[Sarcosine oxidase|Sarcosine oxidase]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:010368302</ref><references group="xtra"/>
+[[Category: Large Structures]]
-[[Category: Bacillus sp.]]
+[[Category: Chen Z]]
-[[Category: Sarcosine oxidase]]
+[[Category: Jorns MS]]
-[[Category: Chen, Z.]]
+[[Category: Mathews FS]]
-[[Category: Jorns, M S.]]
+[[Category: Trickey P]]
-[[Category: Mathews, F S.]]
-[[Category: Trickey, P.]]
-[[Category: Flavoprotein oxidase]]
-[[Category: Inhibitor 2-furoic acid]]
-[[Category: Oxidoreductase]]