2g8l: Difference between revisions

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-[[Image:2g8l.gif|left|200px]]<br /><applet load="2g8l" size="350" color="white" frame="true" align="right" spinBox="true"
-caption="2g8l, resolution 2.040&Aring;" />
-'''Crystal structure of a protein of unknown function from DUF180 family (3258004) from Pyrococcus horikoshii at 2.04 A resolution.'''<br />
-==About this Structure==
+==Crystal structure of a duf89 family protein (ph1575) from pyrococcus horikoshii at 2.04 A resolution==
-G8L is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii] with <scene name='pdbligand=UNL:'>UNL</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G8L OCA].
+<StructureSection load='2g8l' size='340' side='right'caption='[[2g8l]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2g8l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G8L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G8L FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g8l OCA], [https://pdbe.org/2g8l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g8l RCSB], [https://www.ebi.ac.uk/pdbsum/2g8l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g8l ProSAT], [https://www.topsan.org/Proteins/JCSG/2g8l TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/D89S1_PYRHO D89S1_PYRHO] Metal-dependent phosphatase with probable damage-control functions (PubMed:27322068). Shows phosphatase activity against p-nitrophenyl phosphate (pNPP), but natural substrates have not been identified yet (PubMed:27322068). Low phosphatase activity against 8-oxo nucleotides suggests that it could hydrolyze oxidatively damaged purine nucleotides or their biosynthetic intermediates (PubMed:27322068).<ref>PMID:27322068</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g8/2g8l_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g8l ConSurf].
+<div style="clear:both"></div>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Pyrococcus horikoshii]]
-[[Category: Single protein]]
-[[Category: JCSG, Joint Center for Structural Genomics.]]
-[[Category: EDO]]
-[[Category: UNL]]
-[[Category: 3258004]]
-[[Category: hypothetical protein]]
-[[Category: jcsg]]
-[[Category: joint center for structural genomics]]
-[[Category: protein structure initiative]]
-[[Category: psi]]
-[[Category: structural genomics]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:29:11 2008''