2eg9: Difference between revisions

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-[[Image:2eg9.jpg|left|200px]]<br /><applet load="2eg9" size="350" color="white" frame="true" align="right" spinBox="true"
-caption="2eg9, resolution 2.80&Aring;" />
-'''Crystal structure of the truncated extracellular domain of mouse CD38'''<br />
-==About this Structure==
+==Crystal structure of the truncated extracellular domain of mouse CD38==
-EG9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Active as [http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EG9 OCA].
+<StructureSection load='2eg9' size='340' side='right'caption='[[2eg9]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2eg9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EG9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EG9 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eg9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eg9 OCA], [https://pdbe.org/2eg9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eg9 RCSB], [https://www.ebi.ac.uk/pdbsum/2eg9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eg9 ProSAT], [https://www.topsan.org/Proteins/RSGI/2eg9 TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CD38_MOUSE CD38_MOUSE] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eg/2eg9_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eg9 ConSurf].
+<div style="clear:both"></div>
+==See Also==
+*[[Cluster of Differentiation CD38|Cluster of Differentiation CD38]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Mus musculus]]
-[[Category: NAD(+) nucleosidase]]
+[[Category: Hara-Yokoyama M]]
-[[Category: Single protein]]
+[[Category: Kukimoto-Niino M]]
-[[Category: Hara-Yokoyama, M.]]
+[[Category: Mishima C]]
-[[Category: Kukimoto-Niino, M.]]
+[[Category: Shirouzu M]]
-[[Category: Mishima, C.]]
+[[Category: Terada T]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Wakiyama M]]
-[[Category: Shirouzu, M.]]
+[[Category: Yokoyama S]]
-[[Category: Terada, T.]]
-[[Category: Wakiyama, M.]]
-[[Category: Yokoyama, S.]]
-[[Category: cell sueface antigen]]
-[[Category: hydrolase]]
-[[Category: national project on protein structural and functional analyse]]
-[[Category: nppsfa]]
-[[Category: riken structural genomics/proteomics initiative]]
-[[Category: rsgi]]
-[[Category: structural genomic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Mar 14 09:29:58 2008''