1z72: Difference between revisions

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-[[Image:1z72.gif|left|200px]]
- {{Structure
+==Structure of a putative transcriptional regulator from Streptococcus pneumoniae==
-|PDB= 1z72 |SIZE=350|CAPTION= <scene name='initialview01'>1z72</scene>, resolution 1.45&Aring;
+<StructureSection load='1z72' size='340' side='right'caption='[[1z72]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
+<table><tr><td colspan='2'>[[1z72]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z72 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z72 FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
-|GENE= SP0716 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 Streptococcus pneumoniae TIGR4])
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam03070 TENA_THI-4], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0819 TenA]</span>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z72 OCA], [https://pdbe.org/1z72 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z72 RCSB], [https://www.ebi.ac.uk/pdbsum/1z72 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z72 ProSAT], [https://www.topsan.org/Proteins/MCSG/1z72 TOPSAN]</span></td></tr>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z72 OCA], [http://www.ebi.ac.uk/pdbsum/1z72 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1z72 RCSB]</span>
+</table>
-}}
+== Function ==
+[https://www.uniprot.org/uniprot/A0A0H2UP67_STRPN A0A0H2UP67_STRPN] Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).[PIRNR:PIRNR003170]
-'''Structure of a putative transcriptional regulator from Streptococcus pneumoniae'''
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
-==About this Structure==
+  <jmolCheckbox>
-Z72 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z72 OCA].
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z7/1z72_consurf.spt"</scriptWhenChecked>
-[[Category: Single protein]]
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
-[[Category: Streptococcus pneumoniae tigr4]]
+    <text>to colour the structure by Evolutionary Conservation</text>
-[[Category: Abdullah, J.]]
+  </jmolCheckbox>
-[[Category: Cuff, M E.]]
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z72 ConSurf].
-[[Category: Joachimiak, A.]]
+<div style="clear:both"></div>
-[[Category: MCSG, Midwest Center for Structural Genomics.]]
+__TOC__
-[[Category: Zhou, M.]]
+</StructureSection>
-[[Category: mcsg]]
+[[Category: Large Structures]]
-[[Category: midwest center for structural genomic]]
+[[Category: Streptococcus pneumoniae TIGR4]]
-[[Category: protein structure initiative]]
+[[Category: Abdullah J]]
-[[Category: psi]]
+[[Category: Cuff ME]]
-[[Category: streptococcus pneumoniae]]
+[[Category: Joachimiak A]]
-[[Category: structural genomic]]
+[[Category: Zhou M]]
-[[Category: transcription regulator]]
-[[Category: transcriptional regulator]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:17:27 2008''