1y1q: Difference between revisions

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-[[Image:1y1q.gif|left|200px]]<br /><applet load="1y1q" size="350" color="white" frame="true" align="right" spinBox="true"
-caption="1y1q, resolution 2.35&Aring;" />
-'''Crystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium in Complex with Uridine-5p-monophosphate and Sulfate Ion at 2.35A Resolution'''<br />
-==About this Structure==
+==Crystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium in Complex with Uridine-5p-monophosphate and Sulfate Ion at 2.35A Resolution==
-Y1Q is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=U:'>U</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y1Q OCA].
+<StructureSection load='1y1q' size='340' side='right'caption='[[1y1q]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
-[[Category: Salmonella typhimurium]]
+== Structural highlights ==
-[[Category: Single protein]]
+<table><tr><td colspan='2'>[[1y1q]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y1Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y1Q FirstGlance]. <br>
-[[Category: Uridine phosphorylase]]
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
-[[Category: Betzel, C.]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>
-[[Category: Dontsova, M V.]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y1q OCA], [https://pdbe.org/1y1q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y1q RCSB], [https://www.ebi.ac.uk/pdbsum/1y1q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y1q ProSAT]</span></td></tr>
-[[Category: Ealick, S E.]]
+</table>
-[[Category: Gabdoulkhakov, A G.]]
+== Function ==
-[[Category: Kachalova, G S.]]
+[https://www.uniprot.org/uniprot/UDP_SALTY UDP_SALTY] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity).
-[[Category: Mikhailov, A M.]]
+== Evolutionary Conservation ==
-[[Category: SO4]]
+[[Image:Consurf_key_small.gif|200px|right]]
-[[Category: U]]
+Check<jmol>
-[[Category: nucleoside phosphorylase]]
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y1/1y1q_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1y1q ConSurf].
+<div style="clear:both"></div>
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:00:57 2008''
+==See Also==
+*[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
+[[Category: Betzel C]]
+[[Category: Dontsova MV]]
+[[Category: Ealick SE]]
+[[Category: Gabdoulkhakov AG]]
+[[Category: Kachalova GS]]
+[[Category: Mikhailov AM]]