1si5: Difference between revisions

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 <StructureSection load='1si5' size='340' side='right'caption='[[1si5]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1si5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SI5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SI5 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1si5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SI5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SI5 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1si5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1si5 OCA], [https://pdbe.org/1si5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1si5 RCSB], [https://www.ebi.ac.uk/pdbsum/1si5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1si5 ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.53&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1si5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1si5 OCA], [https://pdbe.org/1si5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1si5 RCSB], [https://www.ebi.ac.uk/pdbsum/1si5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1si5 ProSAT]</span></td></tr>
 </table>
 == Disease ==
-[[https://www.uniprot.org/uniprot/HGF_HUMAN HGF_HUMAN]] Defects in HGF are the cause of deafness autosomal recessive type 39 (DFNB39) [MIM:[https://omim.org/entry/608265 608265]]. A form of profound prelingual sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.<ref>PMID:19576567</ref>
+[https://www.uniprot.org/uniprot/HGF_HUMAN HGF_HUMAN] Defects in HGF are the cause of deafness autosomal recessive type 39 (DFNB39) [MIM:[https://omim.org/entry/608265 608265]. A form of profound prelingual sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.<ref>PMID:19576567</ref>
 == Function ==
-[[https://www.uniprot.org/uniprot/HGF_HUMAN HGF_HUMAN]] Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.<ref>PMID:15167892</ref> <ref>PMID:20624990</ref>
+[https://www.uniprot.org/uniprot/HGF_HUMAN HGF_HUMAN] Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.<ref>PMID:15167892</ref> <ref>PMID:20624990</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
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    <jmolCheckbox>
      <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/si/1si5_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 36: / Line 37: @@
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Billeci, K L]]
+[[Category: Billeci KL]]
-[[Category: Eigenbrot, C]]
+[[Category: Eigenbrot C]]
-[[Category: Kirchhofer, D]]
+[[Category: Kirchhofer D]]
-[[Category: Lazarus, R A]]
+[[Category: Lazarus RA]]
-[[Category: Lipari, M T]]
+[[Category: Lipari MT]]
-[[Category: Maun, H R]]
+[[Category: Maun HR]]
-[[Category: Moran, P]]
+[[Category: Moran P]]
-[[Category: Peek, M]]
+[[Category: Peek M]]
-[[Category: Santell, L]]
+[[Category: Santell L]]
-[[Category: Yao, X]]
+[[Category: Yao X]]
-[[Category: Chymotrypsin homology]]
-[[Category: Hormone-growth factor complex]]