1rw1: Difference between revisions

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-{{Seed}}
-[[Image:1rw1.png|left|200px]]
-<!--
+==YFFB (PA3664) PROTEIN==
-The line below this paragraph, containing "STRUCTURE_1rw1", creates the "Structure Box" on the page.
+<StructureSection load='1rw1' size='340' side='right'caption='[[1rw1]], [[Resolution|resolution]] 1.02&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1rw1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RW1 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.02&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-{{STRUCTURE_1rw1|  PDB=1rw1  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rw1 OCA], [https://pdbe.org/1rw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rw1 RCSB], [https://www.ebi.ac.uk/pdbsum/1rw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rw1 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q9HXX5_PSEAE Q9HXX5_PSEAE]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rw/1rw1_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rw1 ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+BACKGROUND: The yffB (PA3664) gene of Pseudomonas aeruginosa encodes an uncharacterized protein of 13 kDa molecular weight with a marginal sequence similarity to arsenate reductase from Escherichia coli. The crystal structure determination of YffB was undertaken as part of a structural genomics effort in order to assist with the functional assignment of the protein. RESULTS: The structure was determined at 1.0 A resolution by single-wavelength anomalous diffraction. The fold is very similar to that of arsenate reductase, which is an extension of the thioredoxin fold. CONCLUSION: Given the conservation of the functionally important residues and the ability to bind glutathione, YffB is likely to function as a GSH-dependent thiol reductase.
-===YFFB (PA3664) PROTEIN===
+Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function.,Teplyakov A, Pullalarevu S, Obmolova G, Doseeva V, Galkin A, Herzberg O, Dauter M, Dauter Z, Gilliland GL BMC Struct Biol. 2004 Mar 8;4:5. PMID:15102337<ref>PMID:15102337</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-<!--
+</div>
-The line below this paragraph, {{ABSTRACT_PUBMED_15102337}}, adds the Publication Abstract to the page
+<div class="pdbe-citations 1rw1" style="background-color:#fffaf0;"></div>
-(as it appears on PubMed at http://www.pubmed.gov), where 15102337 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_15102337}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Large Structures]]
-RW1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RW1 OCA].
+[[Category: Pseudomonas aeruginosa PAO1]]
+[[Category: Dauter M]]
-==Reference==
+[[Category: Dauter Z]]
-Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function., Teplyakov A, Pullalarevu S, Obmolova G, Doseeva V, Galkin A, Herzberg O, Dauter M, Dauter Z, Gilliland GL, BMC Struct Biol. 2004 Mar 8;4:5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15102337 15102337]
+[[Category: Doseeva V]]
-[[Category: Pseudomonas aeruginosa pao1]]
+[[Category: Galkin A]]
-[[Category: Single protein]]
+[[Category: Gilliland GL]]
-[[Category: Dauter, M.]]
+[[Category: Herzberg O]]
-[[Category: Dauter, Z.]]
+[[Category: Obmolova G]]
-[[Category: Doseeva, V.]]
+[[Category: Pullalarevu S]]
-[[Category: Galkin, A.]]
+[[Category: Teplyakov A]]
-[[Category: Gilliland, G L.]]
-[[Category: Herzberg, O.]]
-[[Category: Obmolova, G.]]
-[[Category: Pullalarevu, S.]]
-[[Category: S2F, Structure 2.Function Project.]]
-[[Category: Teplyakov, A.]]
-[[Category: S2f]]
-[[Category: Structural genomic]]
-[[Category: Structure 2 function project]]
-[[Category: Thioredoxin fold]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:14:57 2008''