1of9: Difference between revisions

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-==SOLUTION STRUCTURE OF THE PORE FORMING TOXIN OF ENTAMOEBA HISTOLYTICA (AMOEBAPORE A)==
-<StructureSection load='1of9' size='340' side='right' caption='[[1of9]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+==Solution structure of the pore forming toxin of entamoeba histolytica (Amoebapore A)==
+<StructureSection load='1of9' size='340' side='right'caption='[[1of9]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1of9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Entamoeba_histolytica Entamoeba histolytica]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OF9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OF9 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1of9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Entamoeba_histolytica Entamoeba histolytica]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OF9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OF9 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1of9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1of9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1of9 RCSB], [http://www.ebi.ac.uk/pdbsum/1of9 PDBsum]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1of9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1of9 OCA], [https://pdbe.org/1of9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1of9 RCSB], [https://www.ebi.ac.uk/pdbsum/1of9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1of9 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/PFPA_ENTHI PFPA_ENTHI]] Forms pores in the cytoplasmic membrane of host cells. Has antibacterial activity against M.luteus, no activity against E.coli. Implicated in the cytolytic activity of the parasite.
+[https://www.uniprot.org/uniprot/PFPA_ENTH1 PFPA_ENTH1] Forms pores in the cell membrane of host cells (PubMed:14970207, PubMed:1881907, PubMed:7525351, PubMed:7715451, PubMed:8515772). Has antibacterial activity against M.luteus, no activity against E.coli (PubMed:7715451). Implicated in the cytolytic activity of the parasite (PubMed:7715451).<ref>PMID:14970207</ref> <ref>PMID:1881907</ref> <ref>PMID:7525351</ref> <ref>PMID:7715451</ref> <ref>PMID:8515772</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/of/1of9_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/of/1of9_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1of9 ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
@@ Line 25: / Line 27: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 1of9" style="background-color:#fffaf0;"></div>
 == References ==
 <references/>
@@ Line 30: / Line 33: @@
 </StructureSection>
 [[Category: Entamoeba histolytica]]
-[[Category: Bruhn, H]]
+[[Category: Large Structures]]
-[[Category: Dingley, A J]]
+[[Category: Bruhn H]]
-[[Category: Grotzinger, J]]
+[[Category: Dingley AJ]]
-[[Category: Hecht, O]]
+[[Category: Grotzinger J]]
-[[Category: Leippe, M]]
+[[Category: Hecht O]]
-[[Category: Nuland, N Van]]
+[[Category: Leippe M]]
-[[Category: Schleinkofer, K]]
+[[Category: Schleinkofer K]]
-[[Category: Amoebapore some]]
+[[Category: Van Nuland N]]
-[[Category: Pore forming]]
-[[Category: Saplip]]
-[[Category: Toxin]]