1nmo: Difference between revisions

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-{{Seed}}
-[[Image:1nmo.png|left|200px]]
-<!--
+==Structural genomics, protein ybgI, unknown function==
-The line below this paragraph, containing "STRUCTURE_1nmo", creates the "Structure Box" on the page.
+<StructureSection load='1nmo' size='340' side='right'caption='[[1nmo]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1nmo]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Escherichia_coli_O157:H7 Escherichia coli O157:H7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NMO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NMO FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-{{STRUCTURE_1nmo|  PDB=1nmo  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nmo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nmo OCA], [https://pdbe.org/1nmo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nmo RCSB], [https://www.ebi.ac.uk/pdbsum/1nmo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nmo ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/GCH1L_ECOLI GCH1L_ECOLI] Provides significant protection from radiation damage and may be involved in the degradation of radiation-damaged nucleotides.<ref>PMID:25049088</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nm/1nmo_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nmo ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+BACKGROUND: The protein encoded by the gene ybgI was chosen as a target for a structural genomics project emphasizing the relation of protein structure to function. RESULTS: The structure of the ybgI protein is a toroid composed of six polypeptide chains forming a trimer of dimers. Each polypeptide chain binds two metal ions on the inside of the toroid. CONCLUSION: The toroidal structure is comparable to that of some proteins that are involved in DNA metabolism. The di-nuclear metal site could imply that the specific function of this protein is as a hydrolase-oxidase enzyme.
-===Structural genomics, protein ybgI, unknown function===
+Crystal structure of Escherichia coli protein ybgI, a toroidal structure with a dinuclear metal site.,Ladner JE, Obmolova G, Teplyakov A, Howard AJ, Khil PP, Camerini-Otero RD, Gilliland GL BMC Struct Biol. 2003 Sep 30;3:7. PMID:14519207<ref>PMID:14519207</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-<!--
+</div>
-The line below this paragraph, {{ABSTRACT_PUBMED_14519207}}, adds the Publication Abstract to the page
+<div class="pdbe-citations 1nmo" style="background-color:#fffaf0;"></div>
-(as it appears on PubMed at http://www.pubmed.gov), where 14519207 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_14519207}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Escherichia coli]]
-NMO is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli,_and_escherichia_coli_o157:h7 Escherichia coli, and escherichia coli o157:h7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NMO OCA].
+[[Category: Escherichia coli O157:H7]]
+[[Category: Large Structures]]
-==Reference==
+[[Category: Camerini-Otero RD]]
-<ref group="xtra">PMID:14519207</ref><references group="xtra"/>
+[[Category: Gilliland GL]]
-[[Category: Escherichia coli, and escherichia coli o157:h7]]
+[[Category: Khil PP]]
-[[Category: Camerini-Otero, R D.]]
+[[Category: Ladner JE]]
-[[Category: Gilliland, G L.]]
+[[Category: Obmolova G]]
-[[Category: Khil, P P.]]
+[[Category: Teplyakov A]]
-[[Category: Ladner, J E.]]
-[[Category: Obmolova, G.]]
-[[Category: S2F, Structure 2.Function Project.]]
-[[Category: Teplyakov, A.]]
-[[Category: Hypothetical protein]]
-[[Category: S2f]]
-[[Category: Structural genomic]]
-[[Category: Structure 2 function project]]
-[[Category: Toroidal structure]]
-[[Category: Ybgi]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:36:52 2009''