1lyz: Difference between revisions

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-[[Image:1lyz.gif|left|200px]]<br /><applet load="1lyz" size="350" color="white" frame="true" align="right" spinBox="true"
-caption="1lyz, resolution 2.0&Aring;" />
-'''REAL-SPACE REFINEMENT OF THE STRUCTURE OF HEN EGG-WHITE LYSOZYME'''<br />
-==About this Structure==
+==Real-space refinement of the structure of hen egg-white lysozyme==
-LYZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LYZ OCA].
+<StructureSection load='1lyz' size='340' side='right'caption='[[1lyz]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1lyz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. The October 2011 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''PDB Pioneers''  by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2011_10 10.2210/rcsb_pdb/mom_2011_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LYZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LYZ FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lyz OCA], [https://pdbe.org/1lyz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lyz RCSB], [https://www.ebi.ac.uk/pdbsum/1lyz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lyz ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ly/1lyz_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lyz ConSurf].
+<div style="clear:both"></div>
-==Reference==
+==See Also==
-Real-space refinement of the structure of hen egg-white lysozyme., Diamond R, J Mol Biol. 1974 Jan 25;82(3):371-91. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=4856347 4856347]
+*[[Lysozyme 3D structures|Lysozyme 3D structures]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Gallus gallus]]
-[[Category: Lysozyme]]
+[[Category: Large Structures]]
-[[Category: Single protein]]
+[[Category: PDB Pioneers]]
-[[Category: Blake, C C.F.]]
+[[Category: RCSB PDB Molecule of the Month]]
-[[Category: Diamond, R.]]
+[[Category: Blake CCF]]
-[[Category: North, A C.T.]]
+[[Category: Diamond R]]
-[[Category: Phillips, D C.]]
+[[Category: North ACT]]
-[[Category: hydrolase (o-glycosyl)]]
+[[Category: Phillips DC]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:49:44 2008''