1fl7: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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 ==HUMAN FOLLICLE STIMULATING HORMONE==
-<StructureSection load='1fl7' size='340' side='right' caption='[[1fl7]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
+<StructureSection load='1fl7' size='340' side='right'caption='[[1fl7]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1fl7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FL7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FL7 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1fl7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FL7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FL7 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fl7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fl7 OCA], [http://pdbe.org/1fl7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1fl7 RCSB], [http://www.ebi.ac.uk/pdbsum/1fl7 PDBsum]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fl7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fl7 OCA], [https://pdbe.org/1fl7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fl7 RCSB], [https://www.ebi.ac.uk/pdbsum/1fl7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fl7 ProSAT]</span></td></tr>
 </table>
-== Disease ==
-[[http://www.uniprot.org/uniprot/FSHB_HUMAN FSHB_HUMAN]] Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency (IFSHD) [MIM:[http://omim.org/entry/229070 229070]]. Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men.<ref>PMID:8220432</ref> <ref>PMID:9271483</ref> <ref>PMID:9280841</ref>
 == Function ==
-[[http://www.uniprot.org/uniprot/FSHB_HUMAN FSHB_HUMAN]] Stimulates development of follicle and spermatogenesis in the reproductive organs.
+[https://www.uniprot.org/uniprot/GLHA_HUMAN GLHA_HUMAN]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fl/1fl7_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fl/1fl7_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 32: / Line 32: @@
 ==See Also==
 *[[Follicle-stimulating hormone|Follicle-stimulating hormone]]
-*[[Hormone|Hormone]]
 *[[Human Follicle-Stimulating Hormone Complexed with its Receptor|Human Follicle-Stimulating Hormone Complexed with its Receptor]]
 == References ==
@@ Line 38: / Line 37: @@
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Dias, J A]]
+[[Category: Large Structures]]
-[[Category: Fox, K M]]
+[[Category: Dias JA]]
-[[Category: Roey, P Van]]
+[[Category: Fox KM]]
-[[Category: Cysteine knot]]
+[[Category: Van Roey P]]
-[[Category: Heterodimer]]
-[[Category: Hormone-growth factor complex]]