8smp: Difference between revisions

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8smp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8smp OCA], [https://pdbe.org/8smp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8smp RCSB], [https://www.ebi.ac.uk/pdbsum/8smp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8smp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8smp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8smp OCA], [https://pdbe.org/8smp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8smp RCSB], [https://www.ebi.ac.uk/pdbsum/8smp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8smp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HYAS1_XENLA HYAS1_XENLA] Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate.<ref>PMID:3410156</ref> <ref>PMID:9442026</ref>
== References ==
<references/>
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Latest revision as of 13:00, 9 October 2024

Xenopus laevis hyaluronan synthase 1, UDP-bound, gating loop inserted stateXenopus laevis hyaluronan synthase 1, UDP-bound, gating loop inserted state

Structural highlights

8smp is a 3 chain structure with sequence from Homo sapiens and Xenopus laevis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.4Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

8smp, resolution 3.40Å

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OCA