6fg7: Difference between revisions

No edit summary
No edit summary
 
Line 1: Line 1:


==Crystal structure of the BIR2 ectodomain from Arabidopsis thaliana.==
==Crystal structure of the BIR2 ectodomain from Arabidopsis thaliana.==
<StructureSection load='6fg7' size='340' side='right' caption='[[6fg7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='6fg7' size='340' side='right'caption='[[6fg7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6fg7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FG7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FG7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6fg7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FG7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BIR2, At3g28450, MFJ20.14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fg7 OCA], [http://pdbe.org/6fg7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fg7 RCSB], [http://www.ebi.ac.uk/pdbsum/6fg7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fg7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fg7 OCA], [https://pdbe.org/6fg7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fg7 RCSB], [https://www.ebi.ac.uk/pdbsum/6fg7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fg7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BIR2_ARATH BIR2_ARATH]] Pseudokinases lacking protein kinase activity and unable to bind ATP-analogs (PubMed:24556575). Negative regulator of pathogen-associated molecular patterns- (PAMP-) triggered immunity by limiting BAK1-receptor complex formation in the absence of ligands (PubMed:24388849).<ref>PMID:24388849</ref> <ref>PMID:24556575</ref>
[https://www.uniprot.org/uniprot/BIR2_ARATH BIR2_ARATH] Pseudokinases lacking protein kinase activity and unable to bind ATP-analogs (PubMed:24556575). Negative regulator of pathogen-associated molecular patterns- (PAMP-) triggered immunity by limiting BAK1-receptor complex formation in the absence of ligands (PubMed:24388849).<ref>PMID:24388849</ref> <ref>PMID:24556575</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arath]]
[[Category: Arabidopsis thaliana]]
[[Category: Hohmann, U]]
[[Category: Large Structures]]
[[Category: Hothorn, M]]
[[Category: Hohmann U]]
[[Category: Ectodomain]]
[[Category: Hothorn M]]
[[Category: Leucine rich repeat receptor]]
[[Category: Membrane receptor]]
[[Category: Protein binding]]
[[Category: Pseudokinase]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA