5npn: Difference between revisions
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==Refined structure of cytotoxin I== | ==Refined structure of cytotoxin I== | ||
<StructureSection load='5npn' size='340' side='right'caption='[[5npn | <StructureSection load='5npn' size='340' side='right'caption='[[5npn]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5npn]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5npn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Naja_oxiana Naja oxiana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NPN FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5npn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5npn OCA], [https://pdbe.org/5npn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5npn RCSB], [https://www.ebi.ac.uk/pdbsum/5npn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5npn ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/3SA1_NAJOX 3SA1_NAJOX] This three-finger cytotoxin is a basic protein that interacts and penetrates into the cell membrane, with the tips of all the three loops. Cytotoxins which have a 'Pro-30' (P-type) interacts with membrane stronger that those which have a Ser-28 (S-type). CTI interacts with membrane weaker than CTII. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Naja oxiana]] | [[Category: Naja oxiana]] | ||
[[Category: Arseniev | [[Category: Arseniev AS]] | ||
[[Category: Dubinnyi | [[Category: Dubinnyi MA]] | ||
[[Category: Dubovskii | [[Category: Dubovskii PV]] | ||