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{{STRUCTURE_3oow|  PDB=3oow  |  SCENE=  }}
===Octameric structure of the phosphoribosylaminoimidazole carboxylase catalytic subunit from Francisella tularensis subsp. tularensis SCHU S4.===


==Function==
==Octameric structure of the phosphoribosylaminoimidazole carboxylase catalytic subunit from Francisella tularensis subsp. tularensis SCHU S4.==
[[http://www.uniprot.org/uniprot/Q5NGE9_FRATT Q5NGE9_FRATT]] Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity).[PIRNR:PIRNR001338]  
<StructureSection load='3oow' size='340' side='right'caption='[[3oow]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3oow]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Francisella_tularensis_subsp._tularensis Francisella tularensis subsp. tularensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OOW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3oow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oow OCA], [https://pdbe.org/3oow PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3oow RCSB], [https://www.ebi.ac.uk/pdbsum/3oow PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3oow ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5NGE9_FRATT Q5NGE9_FRATT] Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity).[PIRNR:PIRNR001338]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oo/3oow_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3oow ConSurf].
<div style="clear:both"></div>


==About this Structure==
==See Also==
[[3oow]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Francisella_tularensis_subsp._tularensis Francisella tularensis subsp. tularensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOW OCA].
*[[Phosphoribosylaminoimidazole carboxylase 3D structures|Phosphoribosylaminoimidazole carboxylase 3D structures]]
__TOC__
</StructureSection>
[[Category: Francisella tularensis subsp. tularensis]]
[[Category: Francisella tularensis subsp. tularensis]]
[[Category: Phosphoribosylaminoimidazole carboxylase]]
[[Category: Large Structures]]
[[Category: Anderson, F W.]]
[[Category: Anderson FW]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Edwards A]]
[[Category: Edwards, A.]]
[[Category: Filippova EV]]
[[Category: Filippova, E V.]]
[[Category: Kudritska M]]
[[Category: Kudritska, M.]]
[[Category: Savchenko A]]
[[Category: Savchenko, A.]]
[[Category: Wawrzak Z]]
[[Category: Wawrzak, Z.]]
[[Category: Catalytic subunit]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Francisella tularensis subsp. tularensis schu s4]]
[[Category: Lyase]]
[[Category: Phosphoribosylaminoimidazole carboxylase]]
[[Category: Pure]]
[[Category: Structural genomic]]

Latest revision as of 11:05, 9 October 2024

Octameric structure of the phosphoribosylaminoimidazole carboxylase catalytic subunit from Francisella tularensis subsp. tularensis SCHU S4.Octameric structure of the phosphoribosylaminoimidazole carboxylase catalytic subunit from Francisella tularensis subsp. tularensis SCHU S4.

Structural highlights

3oow is a 8 chain structure with sequence from Francisella tularensis subsp. tularensis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.75Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q5NGE9_FRATT Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity).[PIRNR:PIRNR001338]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3oow, resolution 1.75Å

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OCA
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