3lo1: Difference between revisions

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==Crystal structure of human alpha-defensin 1 (Y16A mutant)==
==Crystal structure of human alpha-defensin 1 (Y16A mutant)==
<StructureSection load='3lo1' size='340' side='right' caption='[[3lo1]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='3lo1' size='340' side='right'caption='[[3lo1]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3lo1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LO1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LO1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3lo1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LO1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LO1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3gny|3gny]], [[3lnz|3lnz]], [[3lo2|3lo2]], [[3lo4|3lo4]], [[3lo9|3lo9]], [[3loe|3loe]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lo1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lo1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lo1 RCSB], [http://www.ebi.ac.uk/pdbsum/3lo1 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lo1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lo1 OCA], [https://pdbe.org/3lo1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lo1 RCSB], [https://www.ebi.ac.uk/pdbsum/3lo1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lo1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DEF1_HUMAN DEF1_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lo/3lo1_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lo/3lo1_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lo1 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3lo1" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Defensin|Defensin]]
*[[Defensin 3D structures|Defensin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lu, W]]
[[Category: Homo sapiens]]
[[Category: Pazgier, M]]
[[Category: Large Structures]]
[[Category: Antibiotic]]
[[Category: Lu W]]
[[Category: Antimicrobial]]
[[Category: Pazgier M]]
[[Category: Antimicrobial peptide]]
[[Category: Antimicrobial protein]]
[[Category: Antiviral defense]]
[[Category: Defensin]]
[[Category: Disulfide bond]]
[[Category: Fungicide]]
[[Category: Hnp1]]
[[Category: Human alpha defensin 1]]
[[Category: Human neutrophil peptide 1]]
[[Category: Phosphoprotein]]
[[Category: Secreted]]

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