3cxg: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(7 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:3cxg.png|left|200px]]


<!--
==Crystal structure of Plasmodium falciparum thioredoxin, PFI0790w==
The line below this paragraph, containing "STRUCTURE_3cxg", creates the "Structure Box" on the page.
<StructureSection load='3cxg' size='340' side='right'caption='[[3cxg]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3cxg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CXG FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3cxg|  PDB=3cxg  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cxg OCA], [https://pdbe.org/3cxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cxg RCSB], [https://www.ebi.ac.uk/pdbsum/3cxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cxg ProSAT]</span></td></tr>
 
</table>
===Crystal structure of Plasmodium falciparum thioredoxin, PFI0790w===
== Function ==
 
[https://www.uniprot.org/uniprot/THIO3_PLAF7 THIO3_PLAF7] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.<ref>PMID:16910770</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
3CXG is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CXG OCA].  
Check<jmol>
[[Category: Plasmodium falciparum 3d7]]
  <jmolCheckbox>
[[Category: Arrowsmith, C H.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cx/3cxg_consurf.spt"</scriptWhenChecked>
[[Category: Bochkarev, A.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Bountra, C.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Cossar, D.]]
  </jmolCheckbox>
[[Category: Edwards, A M.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cxg ConSurf].
[[Category: Hills, T.]]
<div style="clear:both"></div>
[[Category: Hui, R.]]
== References ==
[[Category: Kozieradzki, I.]]
<references/>
[[Category: Lew, J.]]
__TOC__
[[Category: Pizarro, J.]]
</StructureSection>
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Large Structures]]
[[Category: Schapira, M.]]
[[Category: Plasmodium falciparum 3D7]]
[[Category: Wernimont, A K.]]
[[Category: Arrowsmith CH]]
[[Category: Wilkstrom, M.]]
[[Category: Bochkarev A]]
[[Category: Falciparum]]
[[Category: Bountra C]]
[[Category: Malaria]]
[[Category: Cossar D]]
[[Category: Oxidoreductase]]
[[Category: Edwards AM]]
[[Category: Plasmodium]]
[[Category: Hills T]]
[[Category: Sgc]]
[[Category: Hui R]]
[[Category: Structural genomic]]
[[Category: Kozieradzki I]]
[[Category: Structural genomics consortium]]
[[Category: Lew J]]
[[Category: Thioredoxin]]
[[Category: Pizarro J]]
 
[[Category: Schapira M]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:04:26 2009''
[[Category: Wernimont AK]]
[[Category: Wilkstrom M]]

Latest revision as of 10:54, 9 October 2024

Crystal structure of Plasmodium falciparum thioredoxin, PFI0790wCrystal structure of Plasmodium falciparum thioredoxin, PFI0790w

Structural highlights

3cxg is a 2 chain structure with sequence from Plasmodium falciparum 3D7. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

THIO3_PLAF7 Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Nickel C, Rahlfs S, Deponte M, Koncarevic S, Becker K. Thioredoxin networks in the malarial parasite Plasmodium falciparum. Antioxid Redox Signal. 2006 Jul-Aug;8(7-8):1227-39. doi: 10.1089/ars.2006.8.1227. PMID:16910770 doi:http://dx.doi.org/10.1089/ars.2006.8.1227

3cxg, resolution 2.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=3cxg&oldid=4185919"