3cup: Difference between revisions

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'''Unreleased structure'''


The entry 3cup is ON HOLD  until Apr 16 2010
==Crystal structure of the MHC class II molecule I-Ag7 in complex with the peptide GAD221-235==
<StructureSection load='3cup' size='340' side='right'caption='[[3cup]], [[Resolution|resolution]] 3.09&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3cup]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CUP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.09&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cup OCA], [https://pdbe.org/3cup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cup RCSB], [https://www.ebi.ac.uk/pdbsum/3cup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cup ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DCE2_RAT DCE2_RAT] Catalyzes the production of GABA.<ref>PMID:8999827</ref> [https://www.uniprot.org/uniprot/Q31135_MOUSE Q31135_MOUSE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cu/3cup_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cup ConSurf].
<div style="clear:both"></div>


Authors: Corper, A.L., Yoshida, K., Teyton, L., Wilson, I.A.
==See Also==
 
*[[MHC 3D structures|MHC 3D structures]]
Description: Crystal structure of the MHC class II molecule I-Ag7 in complex with the peptide GAD221-235
*[[MHC II 3D structures|MHC II 3D structures]]
 
== References ==
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 12:12:14 2008''
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Corper AL]]
[[Category: Teyton L]]
[[Category: Wilson IA]]
[[Category: Yoshida K]]

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