2rs9: Difference between revisions
New page: '''Unreleased structure''' The entry 2rs9 is ON HOLD Authors: Qin, X., Nagashima, T., Umehara, T., Hayashi, F., Yokoyama, S. Description: Solution structure of the bromodomain of human... |
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==Solution structure of the bromodomain of human BRPF1 in complex with histone H4K5ac peptide== | |||
<StructureSection load='2rs9' size='340' side='right'caption='[[2rs9]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2rs9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RS9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RS9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rs9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rs9 OCA], [https://pdbe.org/2rs9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rs9 RCSB], [https://www.ebi.ac.uk/pdbsum/2rs9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rs9 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref> | |||
==See Also== | |||
*[[Peregrin|Peregrin]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Hayashi F]] | |||
[[Category: Nagashima T]] | |||
[[Category: Qin X]] | |||
[[Category: Umehara T]] | |||
[[Category: Yokoyama S]] | |||