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[[Image:2pyz.jpg|left|200px]]<br /><applet load="2pyz" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2pyz, resolution 1.79&Aring;" />
'''Crystal structure of the complex of proteinase K with auramine at 1.8A resolution'''<br />


==About this Structure==
==Crystal structure of the complex of proteinase K with auramine at 1.8A resolution==
2PYZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Engyodontium_album Engyodontium album] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=NO3:'>NO3</scene> and <scene name='pdbligand=AU4:'>AU4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Peptidase_K Peptidase K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.64 3.4.21.64] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PYZ OCA].
<StructureSection load='2pyz' size='340' side='right'caption='[[2pyz]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
[[Category: Engyodontium album]]
== Structural highlights ==
[[Category: Peptidase K]]
<table><tr><td colspan='2'>[[2pyz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Parengyodontium_album Parengyodontium album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PYZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PYZ FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
[[Category: Bhushan, A.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AU4:4,4-(AMINOMETHYLENE)BIS(N,N-DIMETHYLANILINE)'>AU4</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
[[Category: Kaur, P.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pyz OCA], [https://pdbe.org/2pyz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pyz RCSB], [https://www.ebi.ac.uk/pdbsum/2pyz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pyz ProSAT]</span></td></tr>
[[Category: Sharma, S.]]
</table>
[[Category: Singh, A K.]]
== Function ==
[[Category: Singh, N.]]
[https://www.uniprot.org/uniprot/PRTK_PARAQ PRTK_PARAQ] Hydrolyzes keratin at aromatic and hydrophobic residues.
[[Category: Singh, T P.]]
== Evolutionary Conservation ==
[[Category: Sinha, M.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: AU4]]
Check<jmol>
[[Category: CA]]
  <jmolCheckbox>
[[Category: NO3]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/py/2pyz_consurf.spt"</scriptWhenChecked>
[[Category: enzyme activity]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: inhibition]]
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pyz ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:34:31 2008''
==See Also==
*[[Proteinase 3D structures|Proteinase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Parengyodontium album]]
[[Category: Bhushan A]]
[[Category: Kaur P]]
[[Category: Sharma S]]
[[Category: Singh AK]]
[[Category: Singh N]]
[[Category: Singh TP]]
[[Category: Sinha M]]

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