2pqx: Difference between revisions

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New page: left|200px<br /><applet load="2pqx" size="350" color="white" frame="true" align="right" spinBox="true" caption="2pqx, resolution 1.42Å" /> '''E. coli RNase 1 (in ...
 
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[[Image:2pqx.jpg|left|200px]]<br /><applet load="2pqx" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2pqx, resolution 1.42&Aring;" />
'''E. coli RNase 1 (in vivo folded)'''<br />


==About this Structure==
==E. coli RNase 1 (in vivo folded)==
2PQX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=MES:'>MES</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Enterobacter_ribonuclease Enterobacter ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.6 3.1.27.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PQX OCA].  
<StructureSection load='2pqx' size='340' side='right'caption='[[2pqx]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
[[Category: Enterobacter ribonuclease]]
== Structural highlights ==
<table><tr><td colspan='2'>[[2pqx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PQX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PQX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.42&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pqx OCA], [https://pdbe.org/2pqx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pqx RCSB], [https://www.ebi.ac.uk/pdbsum/2pqx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pqx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RNI_ECOLI RNI_ECOLI] One of the few RNases that cleaves the phosphodiester bond between any two nucleotide. Shows a preference for cytidylic or guanylic acid.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pq/2pqx_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pqx ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Loris, R.]]
[[Category: Loris R]]
[[Category: Messens, J.]]
[[Category: Messens J]]
[[Category: Wyns, L.]]
[[Category: Wyns L]]
[[Category: CA]]
[[Category: MES]]
[[Category: hydrolase]]
[[Category: ribonuclease]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 13:35:07 2008''

Latest revision as of 10:45, 9 October 2024

E. coli RNase 1 (in vivo folded)E. coli RNase 1 (in vivo folded)

Structural highlights

2pqx is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.42Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RNI_ECOLI One of the few RNases that cleaves the phosphodiester bond between any two nucleotide. Shows a preference for cytidylic or guanylic acid.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2pqx, resolution 1.42Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA