2ogg: Difference between revisions

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==Structure of B. subtilis trehalose repressor (TreR) effector binding domain==
==Structure of B. subtilis trehalose repressor (TreR) effector binding domain==
<StructureSection load='2ogg' size='340' side='right' caption='[[2ogg]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2ogg' size='340' side='right'caption='[[2ogg]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ogg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OGG FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ogg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OGG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">treR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Bacillus globigii" Migula 1900])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ogg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogg OCA], [https://pdbe.org/2ogg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ogg RCSB], [https://www.ebi.ac.uk/pdbsum/2ogg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogg ProSAT], [https://www.topsan.org/Proteins/MCSG/2ogg TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ogg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogg OCA], [http://pdbe.org/2ogg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ogg RCSB], [http://www.ebi.ac.uk/pdbsum/2ogg PDBsum], [http://www.topsan.org/Proteins/MCSG/2ogg TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TRER_BACSU TRER_BACSU]] Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer.  
[https://www.uniprot.org/uniprot/TRER_BACSU TRER_BACSU] Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/og/2ogg_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/og/2ogg_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus globigii migula 1900]]
[[Category: Bacillus subtilis]]
[[Category: Borek, D]]
[[Category: Large Structures]]
[[Category: Joachimiak, A]]
[[Category: Borek D]]
[[Category: Krejcirikova, V]]
[[Category: Joachimiak A]]
[[Category: Structural genomic]]
[[Category: Krejcirikova V]]
[[Category: Moy, S F]]
[[Category: Moy SF]]
[[Category: Otwinowski, Z]]
[[Category: Otwinowski Z]]
[[Category: Rezacova, P]]
[[Category: Rezacova P]]
[[Category: Gene repressor]]
[[Category: Mcsg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Sugar binding]]
[[Category: Transcription]]

Latest revision as of 10:44, 9 October 2024

Structure of B. subtilis trehalose repressor (TreR) effector binding domainStructure of B. subtilis trehalose repressor (TreR) effector binding domain

Structural highlights

2ogg is a 1 chain structure with sequence from Bacillus subtilis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.5Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

TRER_BACSU Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2ogg, resolution 2.50Å

Drag the structure with the mouse to rotate

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