2ogg: Difference between revisions

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-[[Image:2ogg.gif|left|200px]]<br /><applet load="2ogg" size="350" color="white" frame="true" align="right" spinBox="true"
-caption="2ogg, resolution 2.50&Aring;" />
-'''Structure of B. subtilis trehalose repressor (TreR) effector binding domain'''<br />
-==About this Structure==
+==Structure of B. subtilis trehalose repressor (TreR) effector binding domain==
-OGG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGG OCA].
+<StructureSection load='2ogg' size='340' side='right'caption='[[2ogg]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+== Structural highlights ==
-==Reference==
+<table><tr><td colspan='2'>[[2ogg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OGG FirstGlance]. <br>
-The crystal structure of the effector-binding domain of the trehalose repressor TreR from Bacillus subtilis 168 reveals a unique quarternary assembly., Rezacova P, Krejcirikova V, Borek D, Moy SF, Joachimiak A, Otwinowski Z, Proteins. 2007 Nov 15;69(3):679-82. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17705272 17705272]
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ogg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogg OCA], [https://pdbe.org/2ogg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ogg RCSB], [https://www.ebi.ac.uk/pdbsum/2ogg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogg ProSAT], [https://www.topsan.org/Proteins/MCSG/2ogg TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TRER_BACSU TRER_BACSU] Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/og/2ogg_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ogg ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Bacillus subtilis]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Borek, D.]]
+[[Category: Borek D]]
-[[Category: Joachimiak, A.]]
+[[Category: Joachimiak A]]
-[[Category: Krejcirikova, V.]]
+[[Category: Krejcirikova V]]
-[[Category: MCSG, Midwest.Center.for.Structural.Genomics.]]
+[[Category: Moy SF]]
-[[Category: Moy, S.F.]]
+[[Category: Otwinowski Z]]
-[[Category: Otwinowski, Z.]]
+[[Category: Rezacova P]]
-[[Category: Rezacova, P.]]
-[[Category: GOL]]
-[[Category: NA]]
-[[Category: SO4]]
-[[Category: gene repressor]]
-[[Category: mcsg]]
-[[Category: midwest center for structural genomics]]
-[[Category: protein structure initiative]]
-[[Category: psi-2]]
-[[Category: structural genomics]]
-[[Category: sugar binding]]
-[[Category: transcription]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 12:40:55 2008''