2go5: Difference between revisions

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OCA

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 ==Structure of signal recognition particle receptor (SR) in complex with signal recognition particle (SRP) and ribosome nascent chain complex==
-<StructureSection load='2go5' size='340' side='right' caption='[[2go5]], [[Resolution|resolution]] 7.40&Aring;' scene=''>
+<SX load='2go5' size='340' side='right' viewer='molstar' caption='[[2go5]], [[Resolution|resolution]] 7.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2go5]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [http://en.wikipedia.org/wiki/Human Human], [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice] and [http://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GO5 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2go5]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GO5 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2go5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2go5 OCA], [http://pdbe.org/2go5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2go5 RCSB], [http://www.ebi.ac.uk/pdbsum/2go5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2go5 ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.4&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2go5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2go5 OCA], [https://pdbe.org/2go5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2go5 RCSB], [https://www.ebi.ac.uk/pdbsum/2go5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2go5 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/SRPRB_MOUSE SRPRB_MOUSE]] Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR. [[http://www.uniprot.org/uniprot/SRP54_CANFA SRP54_CANFA]] Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). [[http://www.uniprot.org/uniprot/SRPR_HUMAN SRPR_HUMAN]] Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system.
+[https://www.uniprot.org/uniprot/SRP19_PONAB SRP19_PONAB] Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity). Binds directly to 7SL RNA (By similarity). Mediates binding of SRP54 to the SRP complex (By similarity).[UniProtKB:J9PAS6]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 13: / Line 14: @@
    <jmolCheckbox>
      <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/go/2go5_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 31: / Line 32: @@
 *[[Ribosomal protein L31|Ribosomal protein L31]]
 *[[Ribosomal protein L35|Ribosomal protein L35]]
-*[[Signal recognition particle protein|Signal recognition particle protein]]
+*[[Signal recognition particle 3D structures|Signal recognition particle 3D structures]]
-*[[Signal recognition particle receptor|Signal recognition particle receptor]]
+*[[Signal recognition particle receptor 3D structures|Signal recognition particle receptor 3D structures]]
 == References ==
 <references/>
 __TOC__
-</StructureSection>
+</SX>
 [[Category: Canis sp]]
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Lk3 transgenic mice]]
+[[Category: Large Structures]]
+[[Category: Mus musculus]]
 [[Category: Triticum sp]]
-[[Category: Beckmann, R]]
+[[Category: Beckmann R]]
-[[Category: Gartmann, M]]
+[[Category: Gartmann M]]
-[[Category: Halic, M]]
+[[Category: Halic M]]
-[[Category: Mielke, T]]
+[[Category: Mielke T]]
-[[Category: Pool, M R]]
+[[Category: Pool MR]]
-[[Category: Schlenker, O]]
+[[Category: Schlenker O]]
-[[Category: Sinning, I]]
+[[Category: Sinning I]]
-[[Category: Ribosome]]
-[[Category: Sr]]
-[[Category: Srp]]
-[[Category: Translation-rna complex]]