2g9i: Difference between revisions

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<StructureSection load='2g9i' size='340' side='right'caption='[[2g9i]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2g9i' size='340' side='right'caption='[[2g9i]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2g9i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arcfu Arcfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G9I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G9I FirstGlance]. <br>
<table><tr><td colspan='2'>[[2g9i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_DSM_4304 Archaeoglobus fulgidus DSM 4304]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G9I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G9I FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cofE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224325 ARCFU])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g9i OCA], [https://pdbe.org/2g9i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g9i RCSB], [https://www.ebi.ac.uk/pdbsum/2g9i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g9i ProSAT], [https://www.topsan.org/Proteins/MCSG/2g9i TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g9i OCA], [https://pdbe.org/2g9i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g9i RCSB], [https://www.ebi.ac.uk/pdbsum/2g9i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g9i ProSAT], [https://www.topsan.org/Proteins/MCSG/2g9i TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/COFE_ARCFU COFE_ARCFU]] Catalyzes the GTP-dependent successive addition of two L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates. May be able to add up to four gamma-linked glutamates, since F420-4 is a species that was isolated from A.fulgidus.<ref>PMID:17669425</ref>
[https://www.uniprot.org/uniprot/COFE_ARCFU COFE_ARCFU] Catalyzes the GTP-dependent successive addition of two L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates. May be able to add up to four gamma-linked glutamates, since F420-4 is a species that was isolated from A.fulgidus.<ref>PMID:17669425</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g9/2g9i_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g9/2g9i_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arcfu]]
[[Category: Archaeoglobus fulgidus DSM 4304]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Edwards, A]]
[[Category: Edwards A]]
[[Category: Evdokimova, E]]
[[Category: Evdokimova E]]
[[Category: Joachimiak, A]]
[[Category: Joachimiak A]]
[[Category: Kudritska, M]]
[[Category: Kudritska M]]
[[Category: Structural genomic]]
[[Category: Nocek B]]
[[Category: Nocek, B]]
[[Category: Savchenko A]]
[[Category: Savchenko, A]]
[[Category: Cofe homolog]]
[[Category: Gamma-glutamyl ligase]]
[[Category: Homolog of f420-0:gamma-glutamyl ligase]]
[[Category: Ligase]]
[[Category: Mcsg]]
[[Category: PSI, Protein structure initiative]]

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