2g3a: Difference between revisions

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==Crystal structure of putative acetyltransferase from Agrobacterium tumefaciens==
The line below this paragraph, containing "STRUCTURE_2g3a", creates the "Structure Box" on the page.
<StructureSection load='2g3a' size='340' side='right'caption='[[2g3a]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2g3a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_fabrum_str._C58 Agrobacterium fabrum str. C58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G3A FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
{{STRUCTURE_2g3a|  PDB=2g3a  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g3a OCA], [https://pdbe.org/2g3a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g3a RCSB], [https://www.ebi.ac.uk/pdbsum/2g3a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g3a ProSAT], [https://www.topsan.org/Proteins/MCSG/2g3a TOPSAN]</span></td></tr>
 
</table>
===Crystal structure of putative acetyltransferase from Agrobacterium tumefaciens===
== Function ==
 
[https://www.uniprot.org/uniprot/ATSE_AGRFC ATSE_AGRFC] Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It prefers glucosamine 6-phosphate or dopamine. It can also use the thialysine, N(8)-acetylspermidine, chloramphenicol, puromycin, polymyxin B, and 4-aminobutyrate ethyl ester.<ref>PMID:23184347</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2G3A is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Agrobacterium_tumefaciens Agrobacterium tumefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3A OCA].  
Check<jmol>
[[Category: Agrobacterium tumefaciens]]
  <jmolCheckbox>
[[Category: Chruszcz, M.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g3/2g3a_consurf.spt"</scriptWhenChecked>
[[Category: Cymborowski, M.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Edwards, A.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Gu, J.]]
  </jmolCheckbox>
[[Category: MCSG, Midwest Center for Structural Genomics.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g3a ConSurf].
[[Category: Mcsg]]
<div style="clear:both"></div>
[[Category: Minor, W.]]
== References ==
[[Category: Savchenko, A.]]
<references/>
[[Category: Xu, X.]]
__TOC__
[[Category: Zheng, H.]]
</StructureSection>
[[Category: Acetylftransferase]]
[[Category: Agrobacterium fabrum str. C58]]
[[Category: Mcsg]]
[[Category: Large Structures]]
[[Category: Midwest center for structural genomic]]
[[Category: Chruszcz M]]
[[Category: Protein structure initiative]]
[[Category: Cymborowski M]]
[[Category: Psi]]
[[Category: Edwards A]]
[[Category: Structural genomic]]
[[Category: Gu J]]
 
[[Category: Joachimiak A]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 10:04:45 2008''
[[Category: Minor W]]
[[Category: Savchenko A]]
[[Category: Xu X]]
[[Category: Zheng H]]

Latest revision as of 10:37, 9 October 2024

Crystal structure of putative acetyltransferase from Agrobacterium tumefaciensCrystal structure of putative acetyltransferase from Agrobacterium tumefaciens

Structural highlights

2g3a is a 1 chain structure with sequence from Agrobacterium fabrum str. C58. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

ATSE_AGRFC Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It prefers glucosamine 6-phosphate or dopamine. It can also use the thialysine, N(8)-acetylspermidine, chloramphenicol, puromycin, polymyxin B, and 4-aminobutyrate ethyl ester.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Kuhn ML, Majorek KA, Minor W, Anderson WF. Broad-substrate screen as a tool to identify substrates for bacterial Gcn5-related N-acetyltransferases with unknown substrate specificity. Protein Sci. 2013 Feb;22(2):222-30. doi: 10.1002/pro.2199. Epub 2012 Dec 17. PMID:23184347 doi:http://dx.doi.org/10.1002/pro.2199

2g3a, resolution 1.90Å

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