1wpw: Difference between revisions

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-[[Image:1wpw.png|left|200px]]
-{{STRUCTURE_1wpw|  PDB=1wpw  |  SCENE=  }}
+==Crystal Structure of IPMDH from Sulfolobus tokodaii==
+<StructureSection load='1wpw' size='340' side='right'caption='[[1wpw]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-===Crystal Structure of IPMDH from Sulfolobus tokodaii===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1wpw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii Sulfurisphaera tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WPW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WPW FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-[[1wpw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii Sulfolobus tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WPW OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wpw OCA], [https://pdbe.org/1wpw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wpw RCSB], [https://www.ebi.ac.uk/pdbsum/1wpw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wpw ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/LEU3_SULTO LEU3_SULTO] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wp/1wpw_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wpw ConSurf].
+<div style="clear:both"></div>
 ==See Also==
 *[[Isopropylmalate dehydrogenase|Isopropylmalate dehydrogenase]]
-[[Category: 3-isopropylmalate dehydrogenase]]
+__TOC__
-[[Category: Sulfolobus tokodaii]]
+</StructureSection>
-[[Category: Hirose, R.]]
+[[Category: Large Structures]]
-[[Category: Moriyama, H.]]
+[[Category: Sulfurisphaera tokodaii]]
-[[Category: Oshima, T.]]
+[[Category: Hirose R]]
-[[Category: Sakurai, M.]]
+[[Category: Moriyama H]]
-[[Category: Sato, T.]]
+[[Category: Oshima T]]
-[[Category: Suzuki, T.]]
+[[Category: Sakurai M]]
-[[Category: Tanaka, N.]]
+[[Category: Sato T]]
-[[Category: Yamagishi, A.]]
+[[Category: Suzuki T]]
-[[Category: Oxidoreductase]]
+[[Category: Tanaka N]]
+[[Category: Yamagishi A]]